Immunotherapy supplanting chemotherapy for upfront treatment of advanced non-small cell lung cancer: what's next?

被引:2
作者
Ilie, Marius [1 ,2 ,3 ,4 ]
Hofman, Paul [1 ,2 ,3 ,4 ]
机构
[1] Univ Cote dAzur, FHU OncoAge, Pasteur Hosp, Lab Clin & Expt Pathol, Nice, France
[2] Univ Cote dAzur, INSERM, U1081, IRCAN, Nice, France
[3] Univ Cote dAzur, UMR CNRS 7284, Nice, France
[4] Univ Cote dAzur, Pasteur Hosp, Hosp Integrated Biobank BB 0033 00025, Nice, France
关键词
HETEROGENEITY; BLOCKADE;
D O I
10.21037/jtd.2017.03.155
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
引用
收藏
页码:E519 / E521
页数:3
相关论文
共 15 条
[1]   Treatment dilemma in the care of older adults with advanced lung cancer [J].
Gajra, Ajeet ;
Anand, Ankit ;
Loh, Kah Poh ;
Mohile, Supriya .
JOURNAL OF THORACIC DISEASE, 2016, 8 (11) :E1497-E1500
[2]   Comparative study of the PD-L1 status between surgically resected specimens and matched biopsies of NSCLC patients reveal major discordances: a potential issue for anti-PD-L1 therapeutic strategies [J].
Ilie, M. ;
Long-Mira, E. ;
Bence, C. ;
Butori, C. ;
Lassalle, S. ;
Bouhlel, L. ;
Fazzalari, L. ;
Zahaf, K. ;
Lalvee, S. ;
Washetine, K. ;
Mouroux, J. ;
Venissac, N. ;
Poudenx, M. ;
Otto, J. ;
Sabourin, J. C. ;
Marquette, C. H. ;
Hofman, V. ;
Hofman, P. .
ANNALS OF ONCOLOGY, 2016, 27 (01) :147-153
[3]   Assessment of the PD-L1 status by immunohistochemistry: challenges and perspectives for therapeutic strategies in lung cancer patients [J].
Ilie, Marius ;
Hofman, Veronique ;
Dietel, Manfred ;
Soria, Jean-Charles ;
Hofman, Paul .
VIRCHOWS ARCHIV, 2016, 468 (05) :511-525
[4]   Mutational heterogeneity in cancer and the search for new cancer-associated genes [J].
Lawrence, Michael S. ;
Stojanov, Petar ;
Polak, Paz ;
Kryukov, Gregory V. ;
Cibulskis, Kristian ;
Sivachenko, Andrey ;
Carter, Scott L. ;
Stewart, Chip ;
Mermel, Craig H. ;
Roberts, Steven A. ;
Kiezun, Adam ;
Hammerman, Peter S. ;
McKenna, Aaron ;
Drier, Yotam ;
Zou, Lihua ;
Ramos, Alex H. ;
Pugh, Trevor J. ;
Stransky, Nicolas ;
Helman, Elena ;
Kim, Jaegil ;
Sougnez, Carrie ;
Ambrogio, Lauren ;
Nickerson, Elizabeth ;
Shefler, Erica ;
Cortes, Maria L. ;
Auclair, Daniel ;
Saksena, Gordon ;
Voet, Douglas ;
Noble, Michael ;
DiCara, Daniel ;
Lin, Pei ;
Lichtenstein, Lee ;
Heiman, David I. ;
Fennell, Timothy ;
Imielinski, Marcin ;
Hernandez, Bryan ;
Hodis, Eran ;
Baca, Sylvan ;
Dulak, Austin M. ;
Lohr, Jens ;
Landau, Dan-Avi ;
Wu, Catherine J. ;
Melendez-Zajgla, Jorge ;
Hidalgo-Miranda, Alfredo ;
Koren, Amnon ;
McCarroll, Steven A. ;
Mora, Jaume ;
Lee, Ryan S. ;
Crompton, Brian ;
Onofrio, Robert .
NATURE, 2013, 499 (7457) :214-218
[5]   Checkpoint Inhibitors in Metastatic EGFR-Mutated Non-Small Cell Lung Cancer A Meta-Analysis [J].
Lee, Chee Khoon ;
Man, Johnathan ;
Lord, Sally ;
Links, Matthew ;
Gebski, Val ;
Mok, Tony ;
Yang, James Chih-Hsin .
JOURNAL OF THORACIC ONCOLOGY, 2017, 12 (02) :403-407
[6]   Quantitative Assessment of the Heterogeneity of PD-L1 Expression in Non-Small-Cell Lung Cancer [J].
McLaughlin, Joseph ;
Han, Gang ;
Schalper, Kurt A. ;
Carvajal-Hausdorf, Daniel ;
Pelekanou, Vasiliki ;
Rehman, Jamaal ;
Velcheti, Vamsidhar ;
Herbst, Roy ;
LoRusso, Patricia ;
Rimm, David L. .
JAMA ONCOLOGY, 2016, 2 (01) :46-54
[7]   A Harmonization Study for the Use of 22C3 PD-L1 Immunohistochemical Staining on Ventana's Platform [J].
Neuman, Tzahi ;
London, Michal ;
Kania-Almog, Juliane ;
Litvin, Anna ;
Zohar, Yaniv ;
Fridel, Ludmila ;
Sandbank, Judith ;
Barshak, Iris ;
Vainer, Gilad W. .
JOURNAL OF THORACIC ONCOLOGY, 2016, 11 (11) :1863-1868
[8]  
Owonikoko TK, 2007, J CLIN ONCOL, V25, P5570, DOI 10.1200/JCO.2007.12.5435
[9]   Long-Term OS for Patients With Advanced NSCLC Enrolled in the KEYNOTE-001 Study of Pembrolizumab [J].
Ramalingam, Suresh ;
Hui, Rina ;
Gandhi, Leena ;
Carcereny, Enric ;
Felip, Enriqueta ;
Ahn, Myung-Ju ;
Eder, Joseph P. ;
Balmanoukian, Ani S. ;
Leighl, Natasha ;
Aggarwal, Charu ;
Horn, Leora ;
Patnaik, Amita ;
Middleton, Gary W. ;
Gubens, Matthew ;
Hellmann, Matthew ;
Soria, Jean-Charles ;
Lubiniecki, Gregory M. ;
Zhang, Jin ;
Piperdi, Bilal ;
Garon, Edward B. .
JOURNAL OF THORACIC ONCOLOGY, 2016, 11 (10) :S241-S242
[10]  
Ratcliffe MJ, 2017, CLIN CANC RES