The enantiomer of cholesterol

被引:63
作者
Westover, EJ [1 ]
Covey, DF [1 ]
机构
[1] Washington Univ, Sch Med, Dept Mol Biol & Pharmacol, St Louis, MO 63110 USA
关键词
cholesterol; enantiomer; ent-cholesterol; enantioselectivity;
D O I
10.1007/s00232-004-0714-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cholesterol plays a variety of significant roles in biological systems. However, the mechanisms by which cholesterol functions remain largely unclear. The enantiomer of cholesterol (ent-cholesterol)-which has identical physical properties, but opposite three-dimensional configuration compared to cholesterol-is a unique tool that can be used to better understand the mechanisms of cholesterol function. We review the literature pertaining to ent-cholesterol, focusing in particular on its use in biological Studies.
引用
收藏
页码:61 / 72
页数:12
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