Synthesis of 5α-androstan-3β,17β-diol from tigogenin

被引：7

作者：

Merlani, M. I. ^{[1
]}

Amiranashvili, L. Sh. ^{[1
]}

Men'shova, N. I. ^{[1
]}

Kemertelidze, E. P. ^{[1
]}

机构：

[1] IG Kutateladze Inst Pharmaceut Chem, Tbilisi, Georgia

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2007年 / 43卷 / 01期

关键词：

3; beta-adiol; 5; alpha-steroids; tigogenin; synthesis;

D O I：

10.1007/s10600-007-0041-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

5 alpha-Androstan-3 beta,17 beta-diol (3b-adiol), a known inhibitor of prostate cancer cell growth, was synthesized from tigogenin. Its structure was confirmed by NMR and IR spectroscopy and mass spectroscopy.

引用

页码：97 / 99

页数：3

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