Circleator: flexible circular visualization of genome-associated data with BioPerl and SVG

被引:26
作者
Crabtree, Jonathan [1 ]
Agrawal, Sonia [1 ]
Mahurkar, Anup [1 ]
Myers, Garry S. [1 ,2 ,3 ,4 ]
Rasko, David A. [1 ,2 ,4 ]
White, Owen [1 ,5 ,6 ]
机构
[1] Univ Maryland, Sch Med, Inst Genome Sci, Baltimore, MD 21201 USA
[2] Univ Maryland, Sch Med, Dept Microbiol & Immunol, Baltimore, MD 21201 USA
[3] Univ Technol Sydney, i3 Inst, Sydney, NSW 2007, Australia
[4] Univ Maryland, Sch Dent, Dept Microbial Pathogenesis, Baltimore, MD 21201 USA
[5] Univ Maryland, Ctr Hlth Related Informat & Bioimaging, College Pk, MD 20740 USA
[6] Univ Maryland, Sch Med, Dept Epidemiol & Publ Hlth, Baltimore, MD 21201 USA
基金
美国国家卫生研究院;
关键词
TOOL;
D O I
10.1093/bioinformatics/btu505
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Circleator is a Perl application that generates circular figures of genome-associated data. It leverages BioPerl to support standard annotation and sequence file formats and produces publication-quality SVG output. It is designed to be both flexible and easy to use. It includes a library of circular track types and predefined configuration files for common use-cases, including. (i) visualizing gene annotation and DNA sequence data from a GenBank flat file, (ii) displaying patterns of gene conservation in related microbial strains, (iii) showing Single Nucleotide Polymorphisms (SNPs) and indels relative to a reference genome and gene set and (iv) viewing RNA-Seq plots.
引用
收藏
页码:3125 / 3127
页数:3
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