High-Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry (HPLC-ESI-MSn) Analysis and Bioactivity Useful for Prevention of "Diabesity" of Allium commutatum Guss

被引：9

作者：

Loizzo, Monica R. ^{[1
]}

Tundis, Rosa ^{[1
]}

Sut, Stefania ^{[2
]}

Dall'Acqua, Stefano ^{[3
]}

Ilardi, Vincenzo ^{[4
]}

Leporini, Mariarosaria ^{[1
]}

Falco, Tiziana ^{[1
]}

Sicari, Vincenzo ^{[5
]}

Bruno, Maurizio ^{[6
]}

机构：

[1] Univ Calabria, Dept Pharm Hlth & Nutr Sci, I-87036 Arcavacata Di Rende, CS, Italy

[2] Univ Padua, Dipartimento Agron Anim Alimenti Risorse Nat & Am, Padua, Italy

[3] Univ Padua, Dept Pharmaceut & Pharmacol Sci, Padua, Italy

[4] Univ Palermo, Dept Earth & Marine Sci, Via Archirafi 26, Palermo, Italy

[5] Mediterranean Univ Reggio Calabria, Dept Agr Sci, I-89123 Reggio Di Calabria, Italy

[6] Univ Palermo, Dept Biol Chem & Pharmaceut Sci & Technol, Viale Sci,Parco Orleans 2, IT-90128 Palermo, Italy

来源：

PLANT FOODS FOR HUMAN NUTRITION | 2020年 / 75卷 / 01期

关键词：

Garlic; Aerial parts; Bulbs; Carbohydrate-hydrolysing enzymes inhibition; Lipase inhibition; Antioxidant activity; NATURAL-PRODUCTS; ANTIOXIDANT; EXTRACT; ANTIBACTERIAL; INHIBITORS; FLAVONOL; OBESITY; PLANTS; ONION; L;

D O I：

10.1007/s11130-019-00782-2

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

This study aimed at evaluating and comparing the chemical profile obtained by HPLC-ESI-MSn analysis, the inhibitory activity of enzymes linked to obesity (alpha-amylase, alpha-glucosidase, and lipase) and the antioxidant properties (DPPH, ABTS, FRAP, and beta-carotene bleaching tests) of ethanol extracts of bulbs (BE) and aerial parts (APE) from Allium commutatum Guss. (known in Italy as "aglio delle isole"). The chemical profile revealed alliin as the main abundant compound with values of 31.5 and 38.8 mg/g extract for BE and APE, respectively. APE is rich also in quercetin (38.5 mg/g extract) and luteolin (31.8 mg/g extract). Bulbs extract exhibited the highest activity as inhibitor of enzymes linked to obesity. Except for DPPH test, APE showed the highest antioxidant potential with IC50 of 7.6 and 56.6 mu g/mL in ABTS and beta-carotene bleaching test after 60 min of incubation, respectively. In conclusion, the present investigation revealed A. commutatum bulbs and aerial parts as a promising source of inhibitors of enzyme linked to the obesity and of antioxidant compounds.

引用

页码：124 / 130

页数：7

共 29 条

[21] Comparative study of antioxidant properties of wild growing and cultivated Allium species [J].