One-pot Mitsunobu-Staudinger preparation of 3-aminocholan-24-oic acid esters from 3-hydroxycholan-24-oic acid esters

被引：42

作者：

Anelli, PL ^{[1
]}

Lattuada, L ^{[1
]}

Uggeri, F ^{[1
]}

机构：

[1] Bracco Ind Chim Spa, Milano Res Ctr, I-20134 Milan, Italy

来源：

SYNTHETIC COMMUNICATIONS | 1998年 / 28卷 / 01期

关键词：

D O I：

10.1080/00397919808005079

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Hydroxycholan-24-oic acid esters are easily converted into the corresponding 3-amino derivatives via Mitsunobu reaction with diphenylphosphoryl azide (DPPA) and Staudinger reduction with PPh3/H2O of the intermediate azido compound in THF.

引用

页码：109 / 117

页数：9

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