Growing antimicrobial resistance of Shigella isolates

被引：97
作者：
Ashkenazi, S
Levy, I
Kazaronovski, V
Samra, Z
机构：
[1] Schneider Childrens Med Ctr Israel, Dept Paediat A, IL-49202 Petah Tiqwa, Israel
[2] Schneider Childrens Med Ctr Israel, Infect Dis Unit, IL-49202 Petah Tiqwa, Israel
[3] Felsenstein Med Res Ctr, Petah Tiqwa, Israel
[4] Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel
[5] Rabin Med Ctr, Dept Clin Microbiol, Petah Tiqwa, Israel
来源：
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2003年 / 51卷 / 02期
关键词：
diarrhoea; shigellosis; antibiotic therapy;
D O I：
10.1093/jac/dkg080
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Appropriate antibiotic treatment of shigellosis depends on identifying resistance patterns. By studying Shigella isolates in central Israel from 1998 to 2000, and comparing with the period 1991-1992, we identified a significantly increased resistance to tetracycline (from 23% to 87%, P < 0.00001), high resistance to trimethoprim-sulfamethoxazole (94%) and ampicillin (85%) and emerging resistance to quinolones (0.5-2%). These data mandate local monitoring of resistance and its consideration in empirical therapy.
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页码：427 / 429
页数：3
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