The effect of cinnamon on A1C among adolescents with type 1 diabetes

被引：65
作者：
Altschuler, Justin A.
Casella, Samuel J.
MacKenzie, Todd A.
Curtis, Kevin M.
机构：
[1] Dartmouth Coll, Hitchcock Med Ctr, Sect Emergency Med, Dept Emergency Med, Lebanon, NH 03756 USA
[2] Dartmouth Coll, Hitchcock Med Ctr, Dept Gen Internal Med, Lebanon, NH 03756 USA
[3] Dartmouth Coll, Hitchcock Med Ctr, Dept Pediat Endocrinol, Lebanon, NH 03756 USA
[4] Dartmouth Coll, Dept Biol Sci, Hanover, NH 03755 USA
来源：
DIABETES CARE | 2007年 / 30卷 / 04期
关键词：
D O I：
10.2337/dc06-1871
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
OBJECTIVE - The purpose of this study was to determine the effect of cinnamon on glycemic control in adolescents with type I diabetes. RESEARCH DESIGN AND METHODS - Using a prospective, double-blind, placebo-controlled design, 72 adolescent type I diabetic subjects were treated in an outpatient setting with cinnamon (1 g/day) or an equivalent-appearing placebo for 90 days. AlC, total daily insulin intake, and adverse events were recorded and compared between groups. RESULTS- There were no significant differences in final AlC (8.8 vs. 8.7,P = 0.88), change in AlC (0.3 vs. 0.0, P = 0.13), total daily insulin intake, or number of hypoglycemic episodes between the cinnamon and placebo arms. CONCLUSIONS - Cinnamon is not effective for improving glycemic control in adolescents With type 1 diabetes.
引用
收藏
页码：813 / 816
页数：4
相关论文
共 19 条
[1]   Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity [J].
Anderson, RA ;
Broadhurst, CL ;
Polansky, MM ;
Schmidt, WF ;
Khan, A ;
Flanagan, VP ;
Schoene, NW ;
Graves, DJ .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2004, 52 (01) :65-70
[2]   Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro [J].
Broadhurst, CL ;
Polansky, MM ;
Anderson, RA .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2000, 48 (03) :849-852
[3]   Clinical and psychological course of diabetes from adolescence to young adulthood - A longitudinal cohort study [J].
Bryden, KS ;
Peveler, RC ;
Stein, A ;
Neil, A ;
Mayou, RA ;
Dunger, DB .
DIABETES CARE, 2001, 24 (09) :1536-1540
[4]   Research on social support in adolescents with IDDM: A critical review [J].
Burroughs, TE ;
Harris, MA ;
Pontious, SL ;
Santiago, JV .
DIABETES EDUCATOR, 1997, 23 (04) :438-448
[5]  
CHENG N, 2004, P 64 SCI SESS ORL FL
[6]   Social support and patient adherence to medical treatment: A meta-analysis [J].
DiMatteo, MR .
HEALTH PSYCHOLOGY, 2004, 23 (02) :207-218
[7]  
Gómez R, 2002, J PEDIATR ENDOCR MET, V15, P1147
[8]   Coping behaviors at diagnosis and in adjustment one year later in children with diabetes [J].
Grey, M ;
Lipman, T ;
Cameron, ME ;
Thurber, FW .
NURSING RESEARCH, 1997, 46 (06) :312-317
[9]   Metformin as an adjunct theraphy in adolescents with type 1 diabetes and insulin resistance [J].
Hamilton, J ;
Cummings, E ;
Zdravkovic, V ;
Finegood, D ;
Daneman, D .
DIABETES CARE, 2003, 26 (01) :138-143
[10]   Regulation of PTP-1 and insulin receptor kinase by fractions from cinnamon: Implications for cinnamon regulation of insulin signalling [J].
Imparl-Radosevich, J ;
Deas, S ;
Polansky, MM ;
Baedke, DA ;
Ingebritsen, TS ;
Anderson, RA ;
Graves, DJ .
HORMONE RESEARCH, 1998, 50 (03) :177-182
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