H9N2 influenza viruses isolated from poultry in Korean live bird markets continuously evolve and cause the severe clinical signs in layers

被引：72

作者：

Kim, Jin A. ^{[1
]}

Cho, Sung Hwan ^{[1
]}

Kim, Hyun Soo ^{[1
]}

Seo, Sang Heui ^{[1
]}

机构：

[1] Chungnam Natl Univ, Immunol Lab, Div Prevent Med, Coll Vet Med, Taejon 305764, South Korea

来源：

VETERINARY MICROBIOLOGY | 2006年 / 118卷 / 3-4期

关键词：

avian influenza virus; H9N2; chicken;

D O I：

10.1016/j.vetmic.2006.07.007

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

H9N2 influenza viruses are endemic in many Asian countries. We demonstrated that H9N2 influenza viruses isolated from poultry in Korean live bird markets are genetically changing and could cause the clinical signs in layers. Genetic analysis showed that Korean avian H9N2 influenza viruses are distinct from H9N2 influenza viruses circulating in poultry in China and Hong Kong. When we infected layers with H9N2 isolates, layers showed about 30% mortality and the reduction of egg productions. Considering that H9N2 influenza virus is one of potential pandemic candidates, the continuous surveillance is needed to monitor avian H9N2 influenza viruses for the poultry industry and humans. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：169 / 176

页数：8

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