A GENOME ASSEMBLY PLATFORM FOR NEXT-GENERATION SEQUENCING TECHNOLOGY

被引：0

作者：

Lu Wenwen ^{[1
]}

Lu Zhiyuan ^{[1
]}

Wang Yaxu ^{[1
]}

Sun Xiao ^{[1
]}

机构：

[1] Southeast Univ, State Key Lab Bioelect, Nanjing 210096, Peoples R China

来源：

IFPT'6: PROGRESS ON POST-GENOME TECHNOLOGIES, PROCEEDINGS | 2009年

关键词：

Genome sequencing; de novo assembly; short read;

D O I：

暂无

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

With the development of the new genomic sequencing technologies, a lot of new assembly algorithms have emerged. This paper summarizes the basic principles of the new assembly algorithms widely recognized internationally and describes a genome assembly platform we developed. The platform integrates 4 main programs designed especially for users to facilitate operation. We compared the performance of the programs mentioned above with assembly results of sequenced reads of Helicobacter acinonychis genome and verified that Velvet is the best assembly algorithm at present according to both cost time and the length of N50.

引用

页码：166 / 167

页数：2

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