Lactococcus lactis subsp lactis JCM 5805 activates natural killer cells via dendritic cells

被引：18

作者：

Suzuki, Hiroaki ^{[1
]}

Ohshio, Konomi ^{[1
]}

Fujiwara, Daisuke ^{[1
]}

机构：

[1] Kirin Brewery Co Ltd, Cent Labs Key Technol, Yokohama, Kanagawa, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2016年 / 80卷 / 04期

关键词：

natural killer cells; dendritic cells; Lactococcus lactis; IFN-GAMMA PRODUCTION; BACTERIAL-DNA; INTERFERON; NK; IL-12; INTERLEUKIN-12; ENHANCEMENT; REQUIREMENT; INDUCTION; INFECTION;

D O I：

10.1080/09168451.2015.1116922

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Lactococcus lactis subsp. lactis JCM 5805 (JCM5805) has been shown to stimulate plasmacytoid dendritic cells (pDC). Here, we investigated the effect of JCM5805 on NK cells. In vitro studies suggested that JCM5805 activated natural killer (NK) cells via dendritic cells including pDC. Furthermore, the oral administration of JCM5805 enhanced the cytotoxic activity of NK cells

引用

页码：798 / 800

页数：3

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