Knockout mutagenesis of the kpsE gene of Campylobacter jejuni 81116 and its involvement in bacterium-host interactions

被引：62
作者：
Bachtiar, Boy M. [1 ]
Coloe, Peter J. [1 ]
Fry, Benjamin N. [1 ]
机构：
[1] RMIT Univ, Bundoora, Vic 3083, Australia
来源：
FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY | 2007年 / 49卷 / 01期
关键词：
Campylobacter jejuni; kpsE gene; bacterium-host interaction;
D O I：
10.1111/j.1574-695X.2006.00182.x
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Campylobacter jejuni is a common cause of bacterial enteritis. The surface capsular polysaccharides are important for this bacterium to survive in the environment, but little is known about their involvement in bacterium-host interactions. This study showed that the C. jejuni capsular polysaccharides play an important role in adherence to and invasion of human embryonic epithelial cells. However, no significant role of capsular polysaccharides was shown in colonization of the chicken gut.
引用
收藏
页码：149 / 154
页数：6
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