Central Mineralocorticoid Receptors and Cardiovascular Disease

被引:13
作者
Sanchez, Elise P. Gomez [1 ]
机构
[1] Univ Mississippi, Med Ctr, Div Endocrinol, Jackson VA Med Ctr, Jackson, MS 39216 USA
基金
美国国家卫生研究院;
关键词
Mineralocorticoid receptor; Cardiovascular disease; Addison disease; rat model; 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1; ALDOSTERONE-SENSITIVE NEURONS; BLOOD-PRESSURE; GLUCOCORTICOID-RECEPTOR; GENE-EXPRESSION; ANGIOTENSIN-II; HEXOSE-6-PHOSPHATE DEHYDROGENASE; HEART-FAILURE; LIVING CELLS; RAT;
D O I
10.1159/000227807
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The mineralocorticoid receptor (MR) is expressed in many cell types throughout the body, including specific neurons, and mediates diverse functions, many of which are just now being appreciated. MR that pertain to the central modulation of cardiovascular function and health are addressed herein. Copyright (C) 2009 S. Karger AG, Basel
引用
收藏
页码:245 / 250
页数:6
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