Engineering chloroplasts: an alternative site for foreign genes, proteins, reactions and products

被引：80

作者：

Bogorad, L ^{[1
]}

机构：

[1] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA

来源：

TRENDS IN BIOTECHNOLOGY | 2000年 / 18卷 / 06期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0167-7799(00)01444-X

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Plant genetic engineering via the nucleus is a mature technology that has been used very productively for research and commercial biotechnology. By contrast, the ability to introduce foreign genes at specific locations on a chloroplast's chromosome has been aquired relatively recently. Certain limitations of nuclear genome transformation methods might be overcome by the site-specific introduction of genes into plastid chromosomes. In addition, plastids, mitochondria and other subcellular organelles might provide more favorable environments than the nuclear-cytoplasmic compartment for certain biochemical reactions and for accumulating large amounts of some gene and enzyme products.

引用

页码：257 / 263

页数：7

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