Cutaneous Adverse Reactions of Anticancer Agents

被引:14
作者
Kaul, Subuhi [1 ]
Kaffenberger, Benjamin H. [2 ]
Choi, Jennifer N. [3 ]
Kwatra, Shawn G. [4 ]
机构
[1] All India Inst Med Sci, Dept Dermatol, New Delhi 110029, India
[2] Ohio State Dermatol, 1328 Dublin Rd,Suite 100, Columbus, OH 43212 USA
[3] Northwestern Univ, Feinberg Sch Med, Robert H Lurie Comprehens Canc Ctr, Dept Dermatol,Div Oncodermatol, 676 North St Clair,Suite 1600, Chicago, IL 60611 USA
[4] Johns Hopkins Univ, Sch Med, 1550 Orleans St,CRB 2 Suite 206, Baltimore, MD 21231 USA
关键词
Skin; Drugs; Cutaneous adverse effects; Anticancer; Chemotherapy; Immunotherapy; HAND-FOOT-SYNDROME; NEUTROPHILIC ECCRINE HIDRADENITIS; PEGYLATED LIPOSOMAL DOXORUBICIN; BREAST-CANCER PATIENTS; TARGETED THERAPIES; CLINICAL PRESENTATION; SKIN REACTIONS; SINGLE-CENTER; CHEMOTHERAPY; INHIBITORS;
D O I
10.1016/j.det.2019.05.013
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Cutaneous adverse effects are one of the most frequently observed adverse reactions with anticancer agents. This has only intensified with newer targeted and immunologic agents that present with a wide array of drug toxicities and skin reactions. The spectrum ranges from benign, localized dermatoses to generalized, life-threatening cutaneous toxicities. Herein, the authors review the cutaneous adverse effects observed with conventional chemotherapy as well as targeted agents, including the emerging immune checkpoint inhibitors, which have been revolutionary in the treatment of many malignancies.
引用
收藏
页码:555 / +
页数:15
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