Cardiac Disease in Childhood Cancer Survivors Risk Prediction, Prevention, and Surveillance: JACC CardioOncology State-of-the-Art Review

被引:59
作者
Leerink, Jan M. [1 ]
de Baat, Esmee C. [2 ]
Feijen, Elizabeth A. M. [2 ]
Bellersen, Louise [3 ]
van Dalen, Elvira C. [2 ]
Grotenhuis, Heynric B. [4 ]
Kapusta, Livia [5 ,6 ]
Kok, Wouter E. M. [1 ]
Loonen, Jacqueline [7 ]
van der Pal, Heleen J. H. [2 ]
Pluijm, Saskia M. F. [2 ]
Teske, Arco J. [8 ]
Mavinkurve-Groothuis, Annelies M. C. [2 ]
Merkx, Remy [9 ]
Kremer, Leontien C. M. [8 ]
机构
[1] Univ Amsterdam, Amsterdam Univ, Dept Cardiol, Med Ctr, Amsterdam, Netherlands
[2] Princess Maxima Ctr, Dept Pediat Oncol, Utrecht, Netherlands
[3] Radboud Univ Nijmegen, Dept Cardiol, Med Ctr, Nijmegen, Netherlands
[4] Univ Utrecht, Wilhelmina Childrens Hosp, Dept Pediat Cardiol, Utrecht, Netherlands
[5] Radboud Univ Nijmegen, Amalia Childrens Hosp, Dept Pediat Cardiol, Med Ctr, Nijmegen, Netherlands
[6] Tel Aviv Univ, Dept Pediat, Sackler Sch Med, Tel Aviv Sourasky Med Ctr,Pediat Cardiol Unit, Tel Aviv, Israel
[7] Radboud Univ Nijmegen, Dept Pediat Hematol & Oncol, Med Ctr, Nijmegen, Netherlands
[8] Univ Utrecht, Dept Cardiol, Med Ctr, Utrecht, Netherlands
[9] Radboud Univ Nijmegen, Med UltraSound Imaging Ctr, Dept Med Imaging, Med Ctr, Nijmegen, Netherlands
来源
JACC: CARDIOONCOLOGY | 2020年 / 2卷 / 03期
关键词
cardiotoxicity; cardiovascular risk factors; childhood cancer survivors; prevention; risk prediction; ANTHRACYCLINE-INDUCED CARDIOTOXICITY; LONG-TERM SURVIVORS; LEFT-VENTRICULAR FUNCTION; ADULT SURVIVORS; HEART-FAILURE; 5-YEAR SURVIVORS; EUROPEAN ASSOCIATION; AMERICAN SOCIETY; FOLLOW-UP; METABOLIC SYNDROME;
D O I
10.1016/j.jaccao.2020.08.006
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Cardiac diseases in the growing population of childhood cancer survivors are of major concern. Cardiotoxicity as a consequence of anthracyclines and chest radiotherapy continues to be relevant in the modern treatment era. Mitoxantrone has emerged as an important treatment-related risk factor and evidence on traditional cardiovascular risk factors in childhood cancer survivors is accumulating. International surveillance guidelines have been developed with the aim to detect and manage cardiac diseases early and prevent symptomatic disease. There is growing interest in risk prediction models to individualize prevention and surveillance. This State-of-the-Art Review summarizes literature from a systematic PubMed search focused on cardiac diseases after treatment for childhood cancer. Here, we discuss the prevalence, risk factors, prevention, risk prediction, and surveillance of cardiac diseases in survivors of childhood cancer. (C) 2020 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation.
引用
收藏
页码:363 / 378
页数:16
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