Acute Kidney Injury in Sepsis: Evidence From Asia

被引：8
|
作者：
Yoshimoto, Kohei [1 ]
Komaru, Yohei [2 ]
Iwagami, Masao [3 ]
Doi, Kent [1 ]
机构：
[1] Univ Tokyo, Dept Acute Med, Tokyo, Japan
[2] Univ Tokyo, Dept Nephrol & Endocrinol, Tokyo, Japan
[3] London Sch Hyg & Trop Med, Dept Noncommunicable Dis Epidemiol, London, England
来源：
SEMINARS IN NEPHROLOGY | 2020年 / 40卷 / 05期
关键词：
Acute kidney injury; sepsis; epidemiology; adsorption; endotoxin adsorption; RENAL-REPLACEMENT THERAPY; CRITICALLY-ILL PATIENTS; CYTOKINE-ADSORBING HEMOFILTER; POLYMYXIN-B HEMOPERFUSION; HIGH-VOLUME HEMOFILTRATION; SEPTIC SHOCK; CONTINUOUS HEMODIAFILTRATION; FAILURE; MORTALITY; OUTCOMES;
D O I：
10.1016/j.semnephrol.2020.08.005
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Acute kidney injury (AKI) is one of the most frequent complications of sepsis. Because sepsis and AKI synergistically worsen the outcomes of critically ill patients, better therapeutics against septic AKI urgently are required. In addition to the complexity of disease mechanisms of both sepsis and AKI, there is substantial regional variation in clinical practice, which further hampers the development of new treatments for septic AKI. To overcome this problem, evidence accumulation is necessary for building the foundation for developing novel septic AKI treatments. This review provides a summary of updated evidence regarding septic AKI from Asian regions. (C) 2020 Elsevier Inc. All rights reserved.
引用
收藏
页码：489 / 497
页数：9
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