Transition metal catalysed alkylation of pyridines and indoles

被引：62

作者：

Grigg, R

Savic, V

机构：

[1] Molec. Innov., Diversity Automat. S., School of Chemistry

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 32期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/S0040-4039(97)01260-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Heating 3- or 4-acetyl pyridine with alkenes in toluene in the presence of 5-10 mol% of RuH2CO(PPh3)(3) afforded the mono- or a mixture of mono- and di-alkylated products in good yield. Alkylation of acetylindole derivatives was also achieved with similar efficiency. (C) 1997 Elsevier Science Ltd.

引用

页码：5737 / 5740

页数：4

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