Phytochemical investigation of Perovskia abrotanoides

被引：41

作者：

Khaliq, Simin ^{[1
]}

Volk, Franz-Josef ^{[1
]}

Frahm, August Wilhelm ^{[1
]}

机构：

[1] Univ Freiburg, Inst Pharmazeut Wissensch, Dept Pharmaceut Chem, D-79104 Freiburg, Germany

来源：

PLANTA MEDICA | 2007年 / 73卷 / 01期

关键词：

Perovskia abrotanoides; Labiatae; tetracyclic diterpenes; NMR spectral assignment;

D O I：

10.1055/s-2006-951766

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The phytochemical investigation of the n-hexane, the EtOAc, and the n-BuOH soluble fractions of the methanolic extract of the arial parts of Perovskia abrotanoides Karelin furnished ten compounds including the two new tetracyclic diterpenes abrotandiol (7) and abrotanone (8) besides the known cirsimaritin (9), hespiriclin (10), rosmarinic acid (11), stigmast-5-en-3 beta-of (12), stigmast-5,22-dien-3 beta-ol (13), stigmast-5-en-3 beta,7 alpha-diol (14), ursolic acid (15) and betulinic acid (16). Compounds 7 and 8 both show a 6,5,6,6 ring skeleton with a trans-1,1 -dimethylcyclohexa- no[ e,b Itetrahydrofu ran element perpendicular to a benzodihydropyran system. The complete structure elucidation of these compounds has been achieved with NMR techniques.

引用

页码：77 / 83

页数：7

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