proton therapy;
Monte Carlo;
Micromegas;
ionization chambers;
position-sensitive detectors;
micropattern gaseous detectors;
VIVO RANGE VERIFICATION;
GASEOUS DETECTOR;
BEAMS;
D O I:
10.1088/0031-9155/61/4/1563
中图分类号:
R318 [生物医学工程];
学科分类号:
0831 ;
摘要:
Modern proton therapy affords control of the delivery of radiotherapeutic dose on fine length and temporal scales. The authors have developed a novel detector technology based on Micromesh Gaseous Structure (Micromegas) that is uniquely tailored for applications using therapeutic proton beams. An implementation of a prototype Micromegas detector for Monte Carlo using Geant4 is presented here. Comparison of simulation results with measurements demonstrates agreement in relative dose along the proton longitudinal dose profile to be 1%. The effect of a radioactive calibration source embedded in the chamber gas is demonstrated by measurements and reproduced by simulations, also at the 1% level. Our Monte Carlo simulations are shown to reproduce the time structure of ionization pulses produced by a double-scattering delivery system.
机构:
Univ Wisconsin Madison, Dept Med Phys, Madison, WI 53705 USAUniv Wisconsin Madison, Dept Med Phys, Madison, WI 53705 USA
Bednarz, Bryan
Lu, Hsiao-Ming
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02108 USA
Harvard Univ, Sch Med, Boston, MA 02108 USAUniv Wisconsin Madison, Dept Med Phys, Madison, WI 53705 USA
Lu, Hsiao-Ming
Engelsman, Martijn
论文数: 0引用数: 0
h-index: 0
机构:
Paul Scherrer Inst, CH-5232 Villigen, SwitzerlandUniv Wisconsin Madison, Dept Med Phys, Madison, WI 53705 USA
机构:
Univ Wisconsin Madison, Dept Med Phys, Madison, WI 53705 USAUniv Wisconsin Madison, Dept Med Phys, Madison, WI 53705 USA
Bednarz, Bryan
Lu, Hsiao-Ming
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA 02108 USA
Harvard Univ, Sch Med, Boston, MA 02108 USAUniv Wisconsin Madison, Dept Med Phys, Madison, WI 53705 USA
Lu, Hsiao-Ming
Engelsman, Martijn
论文数: 0引用数: 0
h-index: 0
机构:
Paul Scherrer Inst, CH-5232 Villigen, SwitzerlandUniv Wisconsin Madison, Dept Med Phys, Madison, WI 53705 USA