Carcinoid heart disease: Diagnosis and management

被引:31
|
作者
Luis, Sushil A. [1 ]
Pellikka, Patricia A. [1 ]
机构
[1] Mayo Clin, Coll Med, Div Cardiovasc Dis, Rochester, MN 55905 USA
关键词
carcinoid; valves; Hedinger syndrome; echocardiography; ENETS CONSENSUS GUIDELINES; BRAIN NATRIURETIC PEPTIDE; CARDIAC-SURGERY; HEPATIC RESECTION; VALVULAR SURGERY; PROGRESSION; STANDARDS; PROGNOSIS; OUTCOMES; CARE;
D O I
10.1016/j.beem.2015.09.005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Hedinger syndrome refers to carcinoid valvular heart disease. The disease is believed to be triggered by vasoactive substances that result in valvular fibrosis. It classically occurs in patients with metastatic carcinoid and preferentially involves the right sided cardiac valves. Affected valves become thickened and retracted, exhibiting regurgitation and sometimes, stenosis. Echocardiography is recommended in patients with carcinoid syndrome and a follow up study is advisable in those who develop a murmur or other symptoms or signs of valvular heart disease. For appropriately selected patients, valve replacement surgery appears to improve outcomes. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:149 / 158
页数:10
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