Automated chromosomes counting systems using deep neural network

被引：0

作者：

Kang, Seungyoung ^{[1
]}

Han, Junghun ^{[1
]}

Chu, Yuseong ^{[1
]}

Lee, Inkyung ^{[2
]}

Joo, Haemi ^{[2
]}

Yang, Sejung ^{[1
]}

机构：

[1] Yonsei Univ, Dept Biomed Engn, Wonju, South Korea

[2] Korea Hydro & Nucl Power, Radiat Hlth Inst, Seoul, South Korea

来源：

2022 INTERNATIONAL CONFERENCE ON ELECTRONICS, INFORMATION, AND COMMUNICATION (ICEIC) | 2022年

关键词：

Deep Learning; Object detection; Chromosome;

D O I：

10.1109/ICEIC54506.2022.9748307

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Karyotyping analysis is an important clinical process used in the process of diagnosing several genetic diseases by analyzing the number or shape of chromosomes. If the number of chromosomes is out of the normal range, it can cause hereditary diseases such as Down syndrome and Edward syndrome. In this study, we employed Faster R-CNN-based model for automated chromosome counting systems and showed a result of 0.914 in average precision [IoU = 0.75]. As a result, it was possible to count chromosomes by detecting each object with a high probability for independent and overlapping chromosomes.

引用

页数：3

共 6 条

[1] Deep Residual Learning for Image Recognition
He, Kaiming
Zhang, Xiangyu
Ren, Shaoqing
Sun, Jian
[J]. 2016 IEEE CONFERENCE ON COMPUTER VISION AND PATTERN RECOGNITION (CVPR), 2016, : 770 - 778
[2] Searching for MobileNetV3
Howard, Andrew
Sandler, Mark
Chu, Grace
Chen, Liang-Chieh
Chen, Bo
Tan, Mingxing
Wang, Weijun
Zhu, Yukun
Pang, Ruoming
Vasudevan, Vijay
Le, Quoc V.
Adam, Hartwig
[J]. 2019 IEEE/CVF INTERNATIONAL CONFERENCE ON COMPUTER VISION (ICCV 2019), 2019, : 1314 - 1324
[3] Paszke A, 2019, ADV NEUR IN, V32
[4] Molecular genetic analysis of Down syndrome
Patterson, David
[J]. HUMAN GENETICS, 2009, 126 (01) : 195 - 214
[5] Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks
Ren, Shaoqing
He, Kaiming
Girshick, Ross
Sun, Jian
[J]. IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE, 2017, 39 (06) : 1137 - 1149
[6] Yan J., 2019, J COMPUTER COMMUNICA, V07, P102

← 1 →