Hemorrhagic hereditary telangiectasia (Rendu-Osler disease) and infectious diseases: An underestimated association

被引：67

作者：

Dupuis-Girod, Sophie

Giraud, Sophie

Decullier, Evelyne

Lesca, Gaetan

Cottin, Vincent

Faure, Frederic

Merrot, Olivier

Saurin, Jean-Christophe

Cordier, Jean-Francois

Plauchu, Henri

机构：

[1] Hop Hotel Dieu, Serv Genet, Hospices Civils Lyon, F-69288 Lyon 02, France

[2] Hop Hotel Dieu, Ctr Reference Malad Rendu Osler, F-69288 Lyon, France

[3] Hop Edouard Herriot, Genet Mol Lab, Lyon, France

[4] Hop Edouard Herriot, Serv Otorhinolaryngol, Lyon, France

[5] Hop Louis Pradel, Serv Pneumol, Lyon, France

[6] Hop Louis Pradel, Ctr Reference Malad Orphelines Pulm, Lyon, France

[7] Hop Croix Rousse, Serv Otorhinolaryngol, F-69317 Lyon, France

[8] Univ Lyon 1, Serv Hepatogastroenterol, Hop Lyon Sud, Hospices Civils Lyon, F-69365 Lyon, France

来源：

CLINICAL INFECTIOUS DISEASES | 2007年 / 44卷 / 06期

关键词：

D O I：

10.1086/511645

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Among 353 patients with hereditary hemorrhagic telangiectasia retrospectively analyzed during the period 1985-2005, we identified 67 cases of severe infection that affected 48 patients (13.6%). Extracerebral infections accounted for 67% of all infections, and most involved Staphylococcus aureus and were associated with prolonged epistaxis. Cerebral infections accounted for 33% of all infections, were mainly due to multiple and anaerobic bacteria, and were associated with the presence of pulmonary arteriovenous malformations and a short duration of epistaxis.

引用

页码：841 / 845

页数：5

共 23 条

[1] Bidirectional regulation of macrophage function by TGF-β
Ashcroft, GS
[J]. MICROBES AND INFECTION, 1999, 1 (15) : 1275 - 1282
[2] Hereditary hemorrhagic telangectasia and spinal infection
Blanco, P
Schaeverbeke, T
Baillet, L
Lequen, L
Bannwarth, B
Dehais, J
[J]. REVUE DE MEDECINE INTERNE, 1998, 19 (12): : 938 - 939
[3] BLANCO P, 2005, 6 HHT SCI C LYON FRA, V54
[4] Doppler ultrasonographic grading of hepatic vascular malformations in hereditary hemorrhagic telangiectasia - Results of extensive screening
Buscarini, E
Danesino, C
Olivieri, C
Lupinacci, G
De Grazia, F
Reduzzi, L
Blotta, P
Gazzaniga, P
Pagella, F
Grosso, M
Pongiglione, G
Buscarini, L
Plauchu, H
Zambelli, A
[J]. ULTRASCHALL IN DER MEDIZIN, 2004, 25 (05): : 348 - 355
[5] Patients with Hereditary Hemorrhagic Telangectasia (HHT) exhibit a deficit of polymorphonuclear cell and monocyte oxidative burst and phagocytosis:: A possible correlation with altered adaptive immune responsiveness in HHT
Cirulli, Anna
Loria, Maria Paola
Dambra, Porzia
Di Serio, Francesca
Ventura, Maria T.
Amati, Luigi
Jirillo, Emilio
Sabba, Carlo
[J]. CURRENT PHARMACEUTICAL DESIGN, 2006, 12 (10) : 1209 - 1215
[6] A new locus for hereditary haemorrhagic telangiectasia (HHT3) maps to chromosome 5
Cole, SG
Begbie, ME
Wallace, GMF
Shovlin, CL
[J]. JOURNAL OF MEDICAL GENETICS, 2005, 42 (07) : 577 - 582
[7] Pulmonary arteriovenous malformations in patients with hereditary hemorrhagic telangiectasia
Cottin, V
Plauchu, H
Bayle, JY
Barthelet, M
Revel, D
Cordier, JF
[J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2004, 169 (09) : 994 - 1000
[8] Epidemiology of sepsis: Recent advances
Danai P.
Martin G.S.
[J]. Current Infectious Disease Reports, 2005, 7 (5) : 329 - 334
[9] TOXIC-SHOCK SYNDROME - EPIDEMIOLOGIC FEATURES, RECURRENCE, RISK-FACTORS, AND PREVENTION
DAVIS, JP
CHESNEY, PJ
WAND, PJ
LAVENTURE, M
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1980, 303 (25) : 1429 - 1435
[10] Recurrent Staphylococcus aureus extracerebral infections complicating hereditary hemorrhagic telangiectasia (Osler-Rendu-Weber disease)
Duval, X
Djendli, S
Le Moing, V
Longuet, P
Barry, B
Leport, C
Vildé, JL
[J]. AMERICAN JOURNAL OF MEDICINE, 2001, 110 (08) : 671 - 672

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