Successful treatment of donor-derived hepatitis C infection in a lung transplant recipient

被引：13
作者：
Theodoropoulos, Nicole [1 ]
Whitson, Bryan A. [2 ]
Martin, Stanley I. [3 ]
Pouch, Stephanie [4 ]
Pope-Harman, Amy [5 ]
机构：
[1] UMass Mem Med Ctr, Dept Med, Div Infect Dis & Immunol, Worcester, MA USA
[2] Ohio State Univ, Dept Surg, Div Cardiac Surg, Columbus, OH 43210 USA
[3] Geisinger Hlth Syst, Divs Infect Dis, Danville, PA USA
[4] OSU, Div Infect Dis, Dept Internal Med, Columbus, OH USA
[5] OSU, Div Pulm Allergy Crit Care & Sleep Med, Dept Internal Med, Columbus, OH USA
来源：
TRANSPLANT INFECTIOUS DISEASE | 2017年 / 19卷 / 02期
关键词：
direct-acting antivirals; donor-derived infection; hepatitis C; lung transplant; HUMAN-IMMUNODEFICIENCY-VIRUS; GENOTYPE; ORGAN; TRANSMISSION; SOFOSBUVIR; SIMEPREVIR; RIBAVIRIN;
D O I：
10.1111/tid.12659
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Data are limited regarding the use of direct-acting antivirals for treatment of hepatitis C infection post lung transplant, especially in a donor-derived infection. We present a case of a lung transplant recipient with donor-derived hepatitis C that was successfully treated with a 12-week regimen of simeprevir and sofosbuvir. This case reiterates the importance of screening recipients of increased-risk donor organs for disease transmission and the value of early therapy.
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页数：3
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