Fatal Curvularia brain abscess in a heart and kidney transplant recipient

被引:5
|
作者
Zamora, Jose Armando Gonzales [1 ]
Varadarajalu, Yogeeta [1 ]
机构
[1] Univ Miami, Dept Med, Div Infect Dis, Miller Sch Med, Miami, FL 33136 USA
来源
IDCASES | 2019年 / 17卷
关键词
Curvularia; Brain abscess; Transplant;
D O I
10.1016/j.idcr.2019.e00576
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
A 42-year-old woman with history of heart failure status post orthotopic heart transplant and end stage renal disease presented to the hospital with decompensated heart failure that progressed to cardiogenic shock. She underwent a new orthotopic heart transplant and cadaveric donor kidney transplant. Three weeks later, she experienced right facial droop and right upper extremity weakness. Computed tomography showed a left frontal cortical lesion with vasogenic edema and a central hemorrhagic component. Given the concern for an angioinvasive mold infection, she was started on voriconazole and amphotericin B. Brain biopsy was performed and histopathology revealed septated hyphae with acute angle branching. Mycology culture isolated Curvularia sp. Unfortunately, her mental status deteriorated with subsequent development of multiorgan failure that led to death. (C) 2019 The Authors. Published by Elsevier Ltd.
引用
收藏
页数:2
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