Analysis and inspection techniques for mouse liver injury based on terahertz spectroscopy

被引：20

作者：

Huang, Pingjie ^{[1
]}

Cao, Yuqi ^{[1
]}

Chen, Jiani ^{[2
]}

Ge, Weiting ^{[2
]}

Hou, Dibo ^{[1
]}

Zhang, Guangxin ^{[1
]}

机构：

[1] Zhejiang Univ, Coll Control Sci & Engn, State Key Lab Ind Control Technol, Hangzhou, Zhejiang, Peoples R China

[2] Zhejiang Univ, Affiliated Hosp 2, Canc Inst, China Natl Minist Educ,Sch Med,Key Lab Canc Preve, Hangzhou 310009, Zhejiang, Peoples R China

来源：

OPTICS EXPRESS | 2019年 / 27卷 / 18期

基金：

中国国家自然科学基金;

关键词：

FLUOROURACIL; ASSOCIATIONS; TISSUE;

D O I：

10.1364/OE.27.026014

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

At present, researchers are exploring biological tissue detection method using terahertz techniques. In this paper, techniques to inspect mouse liver injury by using terahertz spectroscopy were studied. The boxplots were applied to remove abnormal data, and the maximal information coefficient was employed to select crucial features from the absorption coefficient and refractive index spectra. Random Forests and AdaBoost were applied to recognize different levels of liver injury. We found that AdaBoost had better performance on low-level injury classification. This work suggests that terahertz techniques have the potential to detect liver injury at an early stage and evaluate liver treatment strategies. (C) 2019 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

引用

页码：26014 / 26026

页数：13

共 31 条

[1] Liver histology and surgical outcomes after preoperative chemotherapy with fluorouracil plus oxaliplatin in colorectal cancer liver metastases [J].