Cocrystallisation of succinic and fumaric acids with lutidines: a systematic study

被引：48

作者：

Haynes, Delia A. ^{[1
]}

Jones, William

Motherwell, W. D. Samuel

机构：

[1] Univ Cambridge, Dept Chem, Pfizer Inst Pharmaceut Mat Sci, Lensfield Rd, Cambridge CB2 1EW, England

[2] Cambridge Crystallog Data Ctr, Cambridge CB2 1EZ, England

[3] Univ Kwazulu Natal, Sch Chem, ZA-4041 Durban, South Africa

来源：

CRYSTENGCOMM | 2006年 / 8卷 / 11期

关键词：

D O I：

10.1039/b610294h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of cocrystals and salts of succinic and fumaric acids and the isomers of lutidine have been prepared. The crystal structures of six lutidine - succinic acid cocrystals, four lutidine fumarate salts, and two lutidine - fumaric acid cocrystals have been determined. The crystal structures are compared and discussed in the light of similar features, particularly the formation of three-molecule base - acid - base units, which appears to be important for the stability of the crystal. The packing of these units is found to be very sensitive to methyl group position.

引用

页码：830 / 840

页数：11

共 25 条

[1] The Cambridge Structural Database: a quarter of a million crystal structures and rising [J].