New triterpene saponins from flowers of Impatiens balsamina L. and their anti-hepatic fibrosis activity

被引：11

作者：

Li, Qian ^{[1
]}

Cao, Jiaqing ^{[1
]}

Yuan, Weihui ^{[1
]}

Li, Meng ^{[4
]}

Yang, Liguo ^{[1
]}

Sun, Yuanyuan ^{[3
]}

Wang, Xude ^{[1
]}

Zhao, Yuqing ^{[1
,2
]}

机构：

[1] Shenyang Pharmaceut Univ, Dept Tradit Chinese Med, 103 Wenhua Rd, Shenyang 110016, Liaoning, Peoples R China

[2] Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China

[3] Shenyang Pharmaceut Univ, Sch Life Sci & Biopharmaceut, Shenyang 110016, Peoples R China

[4] Shenyang Pharmaceut Univ, Sch Pharm, Shenyang 110016, Peoples R China

来源：

JOURNAL OF FUNCTIONAL FOODS | 2017年 / 33卷

关键词：

Impatiens balsamina L; Triterpene saponins; Anti-hepatic fibrosis activity; DERIVATIVES; COMPOUND; EXTRACT;

D O I：

10.1016/j.jff.2017.03.033

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Impatiens balsamina L. is an edible plant and it has also been used as traditional medicine in Asia. Phytochemical investigations of the Impatiens balsamina L flowers afforded four new triterpene saponins (Balsaminside A-D, 1-4) and six known compounds (5-10) which were first isolated from this plant. The structures were elucidated by extensive spectroscopic methods including NMR (1D and 2D), and HR-ESI-MS. Analysis of the bioassay result showed that all the new compound had significant cytotoxic activity against t-HSC/Cl-6 cells. The result suggested that triterpene saponins from Impatiens balsamina L. are potential functional food ingredients that can be used as new anti-hepatic fibrosis agent. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：188 / 193

页数：6

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