A new seco-friedelolactone acid from the bark and twigs of Itoa orientalis

被引:7
作者
Chai, Xing-Yun [1 ,2 ]
Xu, Zheng-Ren [1 ]
Bai, Chang-Cai [1 ]
Zhou, Fei-Ran [1 ]
Tu, Peng-Fei [1 ]
机构
[1] Peking Univ, Hlth Sci Ctr, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
[2] Chinese Acad Sci, Key Lab Marine Bioresources Sustainable Utilizat, S China Sea Inst Oceanol, Guangzhou, Guangdong, Peoples R China
关键词
Itoa orientalis; seco-Friedelolactone; Itoaic acid; Anti-COX-2; activity; PHENOLIC GLYCOSIDES; GLUCOSIDES; STEMS;
D O I
10.1016/j.fitote.2009.05.014
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new seco-friedelolactone, named itoaic acid, together with 5 known compounds was isolated from the bark and twigs of Itoa orientalis. The structure was elucidated by means of MS, 1D and 2D NMR techniques. Anti-inflammatory activity against COX-2 was evaluated for several compounds from I. orientalis and another Flacourtiaceae plant Xylosma controversum. (c) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码:408 / 410
页数:3
相关论文
共 16 条
[1]   Itosides J-N from Itoa orientalis and structure -: Anti-COX-2 activity relationship of phenolic glycosides [J].
Chai, Xing Yun ;
Song, Yue Lin ;
Xu, Zheng Ren ;
Shi, Hai Ming ;
Bai, Chang Cai ;
Bi, Dan ;
Wen, Jing ;
Li, Fei Fei ;
Tu, Peng Fei .
JOURNAL OF NATURAL PRODUCTS, 2008, 71 (05) :814-819
[2]   Itosides A-I, new phenolic glycosides from Itoa orientalis [J].
Chai, Xing-Yun ;
Xu, Zheng-Ren ;
Ren, Hong-Yan ;
Shi, Hai-Ming ;
Lu, Ya-Nan ;
Li, Fei-Fei ;
Tu, Peng-Fei .
HELVETICA CHIMICA ACTA, 2007, 90 (11) :2176-2185
[3]   Six insecticidal isoryanodane diterpenoids from the bark and twigs of Itoa orientalis [J].
Chai, Xing-Yun ;
Bai, Chang-Cai ;
Shi, Hai-Ming ;
Xu, Zheng-Ren ;
Ren, Hong-Yan ;
Li, Fei-Fei ;
Lu, Ya-Nan ;
Song, Yue-Lin ;
Tu, Peng-Fei .
TETRAHEDRON, 2008, 64 (24) :5743-5747
[4]  
CHAI XY, PLANTA MED, DOI DOI 10.1055/S-00291185542
[5]  
CHAI XY, 2008, J CHIN PHARM SCI, V17, P86
[6]  
Hong-Yan R., 2007, J CHIN PHARM SCI, V16, P218
[7]   Dynamics of complex phthalate liquids. 2. Structural effects of side chains [J].
Kim, YJ ;
Jonas, J .
JOURNAL OF PHYSICAL CHEMISTRY A, 1998, 102 (17) :2778-2784
[8]  
LE CG, 1999, CHIN J MARIN DRUGS, V2, P12
[9]   Constituents from leaves of Scolopia chinensis [J].
Lu, Ya-Nan ;
Xie, Guang-Bo ;
Bi, Dan ;
Shi, Hai-Ming ;
Tu, Peng-Fei .
HELVETICA CHIMICA ACTA, 2008, 91 (05) :825-830
[10]   Stereochemistry of megastigmane glucosides from Glochidion zeylanicum and Alangium premnifolium [J].
Otsuka, H ;
Hirata, E ;
Shinzato, T ;
Takeda, Y .
PHYTOCHEMISTRY, 2003, 62 (05) :763-768