On the Synthesis of Asymmetric and Dissymmetric Amino Analogues of Troger's Base

被引：12

作者：

Artacho, Josep ^{[1
]}

Warnmark, Kenneth ^{[1
]}

机构：

[1] Lund Univ, Dept Chem, S-22100 Lund, Sweden

来源：

SYNTHESIS-STUTTGART | 2009年 / 18期

基金：

瑞典研究理事会;

关键词：

aminations; catalysis; palladium; Troger's base; halogen-lithium exchange; PALLADIUM-CATALYZED SYNTHESIS; ARYL HALIDES; 2,8-DISUBSTITUTED ANALOGS; SUBSTITUTED ANALOGS; DERIVATIVES; AMINATION; ARYLAMINES; MECHANISM; BROMIDES; C-60;

D O I：

10.1055/s-0029-1219617

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Monoamino and diamino analogues of Troger's base have been synthesized by palladium-catalyzed aminations of the corresponding dihalo analogues using low catalyst loadings. Depending on the nature of the dihalo analogue (Br or 1). catalyst loading and the scale of the reaction, monoamino-monohalo and/or diamino analogues of Troger's base were obtained.

引用

页码：3120 / 3126

页数：7

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