Production of c9,t11-and t10,c12-conjugated Linoleic Acids in Humans by Lactobacillus rhamnosus PL60

被引：19
作者：
Lee, Kieun [1 ]
Lee, Yeonhee [1 ]
机构：
[1] Seoul Womens Univ, Dept Biol, Seoul 139744, South Korea
来源：
JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | 2009年 / 19卷 / 12期
关键词：
Conjugated linoleic acid; Lactobacillus rhamnosus; anti-obesity; SERUM-LIPIDS; SUPPLEMENTATION; MASS; FAT;
D O I：
10.4014/jmb.0907.07010
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Lactobacillus rhamnosus PL60 was tested for whether it can produce c9,t11- and t10,c12-conjugated linoleic acids (CLAs) in human. After consumption of L. rhamnosus PL60, L. rhamnosus was detected in feces 1 week after the start of intake. Analysis by gas chromatography showed that concentrations of c9,t11- and t10,c12-CLAs in serum had increased and concentrations of serum leptin had significantly decreased. Results showed that L. rhamnosus PL60 can survive in human intestines and produce CLAs in humans. This is the first report that bacteria can produce CLAs in humans.
引用
收藏
页码：1617 / 1619
页数：3
相关论文
共 11 条
  • [1] Botelho AP, 2008, ARCH LATINOAM NUTR, V58, P156
  • [2] Intestinal bifidobacteria that produce trans-9, trans-11 conjugated linoleic acid:: A fatty acid with antiproliferative activity against human colon SW480 and HT-29 cancer cells
    Coakley, Mairead
    Johnson, Mark C.
    McGrath, Emma
    Rahman, Shafiqur
    Ross, R. Paul
    Fitzgerald, Gerald F.
    Devery, Rosaleen
    Stanton, Catherine
    [J]. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2006, 56 (01): : 95 - 102
  • [3] KEPLER CR, 1966, J BIOL CHEM, V241, P1350
  • [4] LEE HY, 2006, BIOCHIM BIOPHYS ACTA, V1791, P736
  • [5] Effect of supplementation with conjugated linoleic acid on human serum lipids and body fat
    Mougios, V
    Matsakas, A
    Petridou, A
    Ring, S
    Sagredos, A
    Melissopoulou, A
    Tsigilis, N
    Nikolaidis, M
    [J]. JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2001, 12 (10) : 585 - 594
  • [6] Production of conjugated fatty acids by lactic acid bacteria
    Ogawa, J
    Kishino, S
    Ando, A
    Sugimoto, S
    Mihara, K
    Shimizu, S
    [J]. JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2005, 100 (04) : 355 - 364
  • [7] Pariza MW, 2004, AM J CLIN NUTR, V79, p1132S
  • [8] Supplementation with CLA: Isomer incorporation into serum lipids and effect on body fat of women
    Petridou, A
    Mougios, V
    Sagredos, A
    [J]. LIPIDS, 2003, 38 (08) : 805 - 811
  • [9] Rapid identification of 11 human intestinal Lactobacillus species by multiplex PCR assays using group- and species-specific primers derived from the 16S-23S rRNA intergenic spacer region and its flanking 23S rRNA
    Song, YL
    Kato, N
    Liu, CX
    Matsumiya, Y
    Kato, H
    Watanabe, K
    [J]. FEMS MICROBIOLOGY LETTERS, 2000, 187 (02) : 167 - 173
  • [10] Conjugated linoleic acid supplementation for twelve weeks increases lean body mass in obese humans
    Steck, Susan E.
    Chalecki, Allison M.
    Miller, Paul
    Conway, Jason
    Austin, Gregory L.
    Hardin, James W.
    Albright, Craig D.
    Thuillier, Philippe
    [J]. JOURNAL OF NUTRITION, 2007, 137 (05) : 1188 - 1193
12