Clinical Aspects of Invasive Candidiasis in Critically Ill Patients

被引：7
作者：
Pennisi, Mariano [1 ]
Antonelli, Massimo [1 ]
机构：
[1] Univ A Gemelli Gen Hosp, Inst Intens Care & Anaesthesiol, Rome, Italy
来源：
DRUGS | 2009年 / 69卷
关键词：
INTENSIVE-CARE-UNIT; PLACEBO-CONTROLLED TRIAL; BLOOD-STREAM INFECTIONS; AMPHOTERICIN-B; SURGICAL-PATIENTS; ATTRIBUTABLE MORTALITY; DOUBLE-BLIND; FLUCONAZOLE PROPHYLAXIS; SYSTEMIC CANDIDIASIS; HOSPITAL MORTALITY;
D O I：
10.2165/11315590-000000000-00000
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Invasive candidiasis has emerged as an important cause of morbidity and mortality in intensive care unit patients. This short review focuses on many aspects of Candida infection in critically ill patients including epidemiology, impact on mortality, problems related to diagnosis, strategies to identify patients at risk of developing fungal infections, role of prophylaxis and preemptive strategies, empiric treatment and the role of different classes of antifungal drugs. New antifungal agents, specifically new azoles and echinocandins are discussed.
引用
收藏
页码：21 / 28
页数：8
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