Anaphylaxis is a serious and probably lethal systemic reaction. When a trigger cannot be determined, idiopathic anaphylaxis is considered. It can occur as a complication of chronic spontaneous urticaria (CSU). In idiopathic anaphylaxis presenting with frequent attacks, long-term prophylaxis with H1antihistamines and steroid treatment is recommended but rarely effective. Omalizumab, a humanized monoclonal antibody drug that decreases free immunoglobulin E molecules in the circulation, is approved for the treatment of chronic severe persistent allergic asthma and CSU. We report a 15-year-old female patient suffering from CSU concomitant with idiopathic anaphylaxis. Omalizumab at a dose of 300 mg once every 4 weeks was administered for 6 months. The patient has remained asymptomatic during therapy and 3 months after the end of the therapy.
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Istanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, Turkey
Demirturk, Mustafa
Gelincik, Asli
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Istanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, Turkey
Gelincik, Asli
Colakoglu, Bahattin
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Istanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, Turkey
Colakoglu, Bahattin
Dal, Murat
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Istanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, Turkey
Dal, Murat
Buyukozturk, Suna
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Istanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, Turkey
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Rabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
Rabin Med Ctr, Dept Dermatol, Laser Unit, Petah Tiqwa, IsraelRabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
Levi, A.
Tal, Y.
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Hadassah Hebrew Univ, Med Ctr, Allergy & Clin Immunol Unit, Dept Med, Jerusalem, IsraelRabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
Tal, Y.
Dranitzki, Z.
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Hadassah Hebrew Univ, Med Ctr, Allergy & Clin Immunol Unit, Dept Med, Jerusalem, IsraelRabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
Dranitzki, Z.
Shalit, M.
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Hadassah Hebrew Univ, Med Ctr, Allergy & Clin Immunol Unit, Dept Med, Jerusalem, IsraelRabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
Shalit, M.
Enk, C. D.
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Hadassah Hebrew Univ, Med Ctr, Dept Dermatol, Jerusalem, IsraelRabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
机构:
Istanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, Turkey
Demirturk, Mustafa
Gelincik, Asli
论文数: 0引用数: 0
h-index: 0
机构:
Istanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, Turkey
Gelincik, Asli
Colakoglu, Bahattin
论文数: 0引用数: 0
h-index: 0
机构:
Istanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, Turkey
Colakoglu, Bahattin
Dal, Murat
论文数: 0引用数: 0
h-index: 0
机构:
Istanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, Turkey
Dal, Murat
Buyukozturk, Suna
论文数: 0引用数: 0
h-index: 0
机构:
Istanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Div Allergy, Dept Internal Med, Istanbul, Turkey
机构:
Rabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
Rabin Med Ctr, Dept Dermatol, Laser Unit, Petah Tiqwa, IsraelRabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
Levi, A.
Tal, Y.
论文数: 0引用数: 0
h-index: 0
机构:
Hadassah Hebrew Univ, Med Ctr, Allergy & Clin Immunol Unit, Dept Med, Jerusalem, IsraelRabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
Tal, Y.
Dranitzki, Z.
论文数: 0引用数: 0
h-index: 0
机构:
Hadassah Hebrew Univ, Med Ctr, Allergy & Clin Immunol Unit, Dept Med, Jerusalem, IsraelRabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
Dranitzki, Z.
Shalit, M.
论文数: 0引用数: 0
h-index: 0
机构:
Hadassah Hebrew Univ, Med Ctr, Allergy & Clin Immunol Unit, Dept Med, Jerusalem, IsraelRabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel
Shalit, M.
Enk, C. D.
论文数: 0引用数: 0
h-index: 0
机构:
Hadassah Hebrew Univ, Med Ctr, Dept Dermatol, Jerusalem, IsraelRabin Med Ctr, Dept Dermatol, Photodermatosis Clin, Petah Tiqwa, Israel