OXALIPLATIN INDUCED PULMONARY FIBROSIS: A CASE REPORT

被引：2

作者：

Pavlovic, Mirjana ^{[1
]}

Separovic, Robert ^{[1
]}

Silovski, Tajana ^{[1
]}

Vuger, Ana Tecic ^{[1
]}

Juric, Andreja ^{[1
]}

机构：

[1] Univ Hosp Tumors, Dept Med Oncol, Sestre Milosrdnice Univ Hosp Ctr, Ilica 197, HR-10000 Zagreb, Croatia

来源：

ACTA CLINICA CROATICA | 2020年 / 59卷 / 04期

关键词：

Oxaliplatin; Colon cancer; Side effects; Pulmonary fibrosis; Interstitial lung disease;

D O I：

10.20471/acc.2020.59.04.25

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Oxaliplatin is part of the standard chemotherapy regimens for treating colorectal carcinoma. Pulmonary fibrosis is a serious but rare side effect of oxaliplatin treatment, which resulted in patient death in more than half of the reported cases. The precise pathophysiological mechanism of this phenomenon has not been clarified yet. Analysis of the reported cases strongly suggests that early diagnosis and immediate corticosteroid treatment are crucial for better prognosis. Here we report a case of pulmonary fibrosis related to the FOLFOX regimen in a patient with early colorectal carcinoma.

引用

页码：761 / 764

页数：4

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