Copper-Catalyzed Successive C-C bond formations on Indoles or Pyrrole: A Convergent Synthesis of Symmetric and Unsymmetric Hydroxyl Substituted N-H Carbazoles

被引：23

作者：

Qiao, Yu ^{[1
]}

Wu, Xin-Xing ^{[1
]}

Zhao, Yupeng ^{[1
]}

Sun, Yongqing ^{[1
]}

Li, Baoguo ^{[1
]}

Chen, Shufeng ^{[1
]}

机构：

[1] Inner Mongolia Univ, Coll Chem & Chem Engn, Inner Mongolia Key Lab Fine Organ Synth, Hohhot 010021, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2018年 / 360卷 / 11期

基金：

中国国家自然科学基金;

关键词：

hydroxyl substituted N-H carbazoles; C-C bond formation; copper; indoles; pyrrole; HIGHLY EFFICIENT; SELECTIVE SYNTHESIS; 1ST SYNTHESIS; DERIVATIVES; HYDROACYLATION; BENZANNULATION; ALKALOIDS; MIGRATION; ALKYNES; FACILE;

D O I：

10.1002/adsc.201800154

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A novel copper-catalyzed successive C-Cbond formations on indoles and pyrrole approach for the direct synthesis of hydroxyl substituted N-H carbazoles is described. The current process represents an atom-economical method for the preparation of both symmetric and unsymmetric densely substituted and hydroxyl containing N-H carbazoles from easily accessible starting materials without the need for expensive metals and harsh reaction conditions.

引用

页码：2138 / 2143

页数：6

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