Endoscopic ultrasound in pancreatic cancer treatment: Facts and hopes

被引:5
作者
Moutinho-Ribeiro, Pedro
Liberal, Rodrigo
Macedo, Guilherme
机构
[1] Porto Training Ctr, Ctr Hosp Sao Joao, Gastroenterol & Hepatol Dept, Porto, Portugal
[2] Porto Training Ctr, WGO, Porto, Portugal
关键词
CELIAC PLEXUS NEUROLYSIS; GUIDED RADIOFREQUENCY ABLATION; MALIGNANT BILIARY OBSTRUCTION; EXPANDABLE METAL STENT; FINE-NEEDLE INJECTION; HIGH OPERATIVE RISK; PHOTODYNAMIC THERAPY; GANGLIA NEUROLYSIS; STEREOTACTIC RADIOSURGERY; PERCUTANEOUS DRAINAGE;
D O I
10.1016/j.clinre.2019.02.014
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Pancreatic ductal adenocarcinoma is one of the most common causes of cancer-related deaths. Since most patients present with advanced disease, its prognosis is dismal. New and more effective therapeutic strategies are needed. Endoscopic ultrasound is currently an indispensable tool for the diagnosis and staging of pancreatic ductal adenocarcinoma. In recent years, endoscopic ultrasound has evolved to become also a therapeutic procedure. On one hand, the role of endoscopic ultrasound in the management of pancreatic cancer-related symptoms (pain, obstructive jaundice, and gastric outlet obstruction) is now well established. On the other hand, its use as a mean to the delivery of anti-tumor therapies (injecting anti-tumor agents, assisting in radiotherapy, and guiding ablative therapies) is still mostly experimental, despite growing evidence supporting its feasibility, safety and efficacy. (C) 2019 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:513 / 521
页数:9
相关论文
共 82 条
[1]   Advances in the Genetics and Biology of Pancreatic Cancer [J].
Aguirre, Andrew J. ;
Collisson, Eric A. .
CANCER JOURNAL, 2017, 23 (06) :315-320
[2]   Feasibility and safety of EUS-guided cryothermal ablation in patients with locally advanced pancreatic cancer [J].
Arcidiacono, Paolo Giorgio ;
Carrara, Silvia ;
Reni, Michele ;
Petrone, Maria Chiara ;
Cappio, Stefano ;
Balzano, Gianpaolo ;
Boemo, Cinzia ;
Cereda, Stefano ;
Nicoletti, Roberto ;
Enderle, Markus Dominik ;
Neugebauer, Alexander ;
von Renteln, Daniel ;
Eickhoff, Axel ;
Testoni, Pier Alberto .
GASTROINTESTINAL ENDOSCOPY, 2012, 76 (06) :1142-1151
[3]   Biliary Drainage in Patients With Unresectable, Malignant Obstruction Where ERCP Fails Endoscopic Ultrasonography-Guided Choledochoduodenostomy Versus Percutaneous Drainage [J].
Artifon, Everson L. A. ;
Aparicio, Dayse ;
Paione, Jose B. ;
Lo, Simon K. ;
Bordini, Andre ;
Rabello, Carolina ;
Otoch, Jose P. ;
Gupta, Kapil .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 2012, 46 (09) :768-774
[4]  
Artifon ELA, 2011, J PANCREAS, V12, P610
[5]   EUS visualization and direct celiac ganglia neurolysis predicts better pain relief in patients with pancreatic malignancy [J].
Ascunce, Gil ;
Ribeiro, Afonso ;
Reis, Isildinha ;
Rocha-Lima, Caio ;
Sleeman, Danny ;
Merchan, Jaime ;
Levi, Joe .
GASTROINTESTINAL ENDOSCOPY, 2011, 73 (02) :267-274
[6]   Comparison of endosonography-guided vs. percutaneous biliary stenting when papilla is inaccessible for ERCP [J].
Bapaye, Amol ;
Dubale, Nachiket ;
Aher, Advay .
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL, 2013, 1 (04) :285-293
[7]   Photodynamic therapy for cancer of the pancreas [J].
Bown, SG ;
Rogowska, AZ ;
Whitelaw, DE ;
Lees, WR ;
Lovat, LB ;
Ripley, P ;
Jones, L ;
Wyld, P ;
Gillams, A ;
Hatfield, AWR .
GUT, 2002, 50 (04) :549-557
[8]   EUS-guided photodynamic therapy of the pancreas: a pilot study [J].
Chan, HH ;
Nishioka, NS ;
Mino, M ;
Lauwers, GY ;
Puricelli, WP ;
Collier, KN ;
Brugge, WR .
GASTROINTESTINAL ENDOSCOPY, 2004, 59 (01) :95-99
[9]  
Chang KJ, 2000, CANCER-AM CANCER SOC, V88, P1325, DOI 10.1002/(SICI)1097-0142(20000315)88:6<1325::AID-CNCR8>3.0.CO
[10]  
2-T