Renal Function: Guardian of Immune Homeostasis

被引：1

作者：

Bruckner, Katja ^{[1
,2
,3
]}

机构：

[1] Univ Calif San Francisco, Eli & Edythe Broad Ctr Regenerat Med & Stem Cell, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Dept Cell & Tissue Biol, San Francisco, CA 94143 USA

[3] Univ Calif San Francisco, Cardiovasc Res Inst, San Francisco, CA 94143 USA

来源：

IMMUNITY | 2019年 / 51卷 / 04期

基金：

美国国家卫生研究院;

关键词：

RECEPTOR;

D O I：

10.1016/j.immuni.2019.09.017

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Microbial cell components from the intestinal microbiota spread systemically in a healthy host, posing the threat of inappropriate immune activation. In this issue of Immunity, Troha et al. identify a key role for renal function in the clearance of circulating Lys-type peptidoglycan, revealing a mechanism that keeps these inflammatory triggers in check to maintain systemic immune homeostasis.

引用

页码：596 / 598

页数：3

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