Type 2 inflammation in eosinophilic chronic obstructive pulmonary disease

被引：52

作者：

Higham, Andrew ^{[1
]}

Beech, Augusta ^{[1
,2
]}

Wolosianka, Sophie ^{[2
]}

Jackson, Natalie ^{[2
]}

Long, Gabriella ^{[1
]}

Kolsum, Umme ^{[1
]}

Southworth, Thomas ^{[2
]}

Pham, Tuyet-Hang ^{[3
]}

Sridhar, Sriram ^{[4
]}

McCrae, Christopher ^{[3
]}

Newbold, Paul ^{[5
]}

Singh, Dave ^{[1
,2
]}

机构：

[1] Univ Manchester, Manchester Univ NHS Foundat Trust, Div Infect Immun & Resp Med,Sch Biol Sci, Manchester Acad Hlth Sci Ctr,Fac Biol Med & Hlth, Manchester, Lancs, England

[2] Med Evaluat Unit, Manchester, Lancs, England

[3] AstraZeneca, Res & Early Dev, Early Resp & Immunol, Translat Sci & Expt Med, Gaithersburg, MD USA

[4] AstraZeneca, Oncol R&D, Translat Sci, Gaithersburg, MD USA

[5] AstraZeneca, Biopharmaceut Med, Gaithersburg, MD USA

来源：

ALLERGY | 2021年 / 76卷 / 06期

关键词：

D O I：

10.1111/all.14661

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：1861 / 1864

页数：4

共 6 条

[1] IL-13-induced changes in the goblet cell density of human bronchial epithelial cell cultures: MAP kinase and phosphatidylinositol 3-kinase regulation [J].

Atherton, HC ;

Jones, G ;

Danahay, H .

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2003, 285 (03) :L730-L739

[2] Asthma-COPD Overlap [J].

Christenson, Stephanie A. ;

Steiling, Katrina ;

van den Berge, Maarten ;

Hijazi, Kahkeshan ;

Hiemstra, Pieter S. ;

Postma, Dirkje S. ;

Lenburg, Marc E. ;

Spira, Avrum ;

Woodruff, Prescott G. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 191 (07) :758-766

[3] Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma [J].

George, Leena ;

Taylor, Adam R. ;

Esteve-Codina, Anna ;

Soler Artigas, Maria ;

Andri Thun, Gian ;

Bates, Stewart ;

Pavlidis, Stelios ;

Wagers, Scott ;

Boland, Anne ;

Prasse, Antje ;

Boschetto, Piera ;

Parr, David G. ;

Nowinski, Adam ;

Barta, Imre ;

Hohlfeld, Jens ;

Greulich, Timm ;

van den Berge, Maarten ;

Hiemstra, Pieter S. ;

Timens, Wim ;

Hinks, Timothy ;

Wenzel, Sally ;

Siddiqui, Salman ;

Richardson, Matthew ;

Venge, Per ;

Heath, Simon ;

Gut, Ivo ;

Tobin, Martin D. ;

Edwards, Lindsay ;

Riley, John H. ;

Djukanovic, Ratko ;

Auffray, Charles ;

De-Meulder, Bertrand ;

Erik-Dahlen, Sven ;

Adcock, Ian M. ;

Chung, Kian Fan ;

Ziegler-Heitbrock, Loems ;

Sterk, Peter J. ;

Singh, Dave ;

Brightling, Christopher E. .

ALLERGY, 2020, 75 (02) :370-380

[4] Pulmonary inflammation in patients with chronic obstructive pulmonary disease with higher blood eosinophil counts [J].

Kolsum, Umme ;

Damera, Gautam ;

Pham, Tuyet-Hang ;

Southworth, Thomas ;

Mason, Sarah ;

Karur, Pradeep ;

Newbold, Paul ;

Singh, Dave .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2017, 140 (04) :1181-+

[5] Blood Eosinophil Counts in Clinical Trials for Chronic Obstructive Pulmonary Disease [J].

Singh, Dave ;

Bafadhel, Mona ;

Brightling, Christopher E. ;

Sciurba, Frank C. ;

Curtis, Jeffrey L. ;

Martinez, Fernando J. ;

Pasquale, Cara B. ;

Merrill, Debora D. ;

Metzdorf, Norbert ;

Petruzzelli, Stefano ;

Tal-Singer, Ruth ;

Compton, Christopher ;

Rennard, Stephen ;

Martin, Ubaldo J. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2020, 202 (05) :660-671

[6] T-helper Type 2-driven Inflammation Defines Major Subphenotypes of Asthma [J].

Woodruff, Prescott G. ;

Modrek, Barmak ;

Choy, David F. ;

Jia, Guiquan ;

Abbas, Alexander R. ;

Ellwanger, Almut ;

Arron, Joseph R. ;

Koth, Laura L. ;

Fahy, John V. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 180 (05) :388-395

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