Evaluating the Affective Component of the Cerebellar Cognitive Affective Syndrome

被引：1
|
作者：
Wolf, Uri
Rapoport, Mark J. [1 ]
Schweizer, Tom A. [2 ,3 ]
机构：
[1] Univ Toronto, Sunnybrook Hlth Sci Ctr, Dept Psychiat, Toronto, ON, Canada
[2] Univ Toronto, Dept Surg, Div Neurosurg, Toronto, ON, Canada
[3] St Michaels Hosp, Dept Neurosurg, Li Ka Shing Knowledge Inst, Kennan Res Ctr, Toronto, ON M5B 1W8, Canada
来源：
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2009年 / 21卷 / 03期
关键词：
MACHADO-JOSEPH-DISEASE; OLIVOPONTOCEREBELLAR ATROPHY; MAJOR DEPRESSION; RATING-SCALE; CHILDREN; SCHIZOPHRENIA; DISORDERS; ATAXIA; DEFICITS; LESIONS;
D O I：
10.1176/jnp.2009.21.3.245
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The authors performed a systematic review and meta-analysis of studies evaluating the affective component of the cerebellar cognitive affective syndrome. Depressive and anxiety symptoms and personality changes were more frequent in patients with spinocerebellar ataxia. Patients with cerebellar lesions were more likely to have depression, deficits in the ability to experience emotions, and behavioral difficulties. A meta-analysis revealed modestly higher scores on the Hamilton Depression Rating Scale (HAM-D) among patients with cerebellar disease. This review highlights the need for cohort studies using noncerebellar comparison groups, more sensitive measures, and appropriate-sized populations with isolated cerebellar lesions to thoroughly assess the affective component of the cerebellar cognitive affective syndrome. (The Journal of Neuropsychiatry and Clinical Neurosciences 2009; 21: 245-253)
引用
收藏
页码：245 / 253
页数：9
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