The Role of Inflammation in Preeclampsia

被引：0
作者：
Sezik, M. [1 ]
机构：
[1] Suleyman Demirel Univ, Fac Med, Dept Obstet & Gynecol, TR-32200 Isparta, Turkey
来源：
PROCEEDINGS OF THE XXI EUROPEAN CONGRESS OF PERINATAL MEDICINE | 2008年
关键词：
PREGNANCY; MAGNESIUM; LEUKOCYTOSIS;
D O I：
暂无
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Preeclampsia is a syndrome with exaggeration of physiological systemic inflammation of pregnancy. Placenta seems to be the initial stimulus for activation of systemic inflammation. However, the presence of pre-pregnancy chronic inflammation is also a determining factor. This could explain why women with pre-existing hypertension, insulin resistance and increased body-mass index have increased risks of preeclampsia and vice versa. Investigations on limiting the inflammatory response by treating maternal infections or novel anti-inflammatory interventions to reduce the incidence or severity of preeclampsia are warranted.
引用
收藏
页码：389 / 392
页数：4
相关论文
共 16 条
  • [1] Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis
    Bellamy, Leanne
    Casas, Juan-Pablo
    Hingorani, Aroon D.
    Williams, David J.
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2007, 335 (7627): : 974 - 977
  • [2] Magnesium maintains endothelial integrity, up-regulates proteolysis of ultra-large von Willebrand factor, and reduces platelet aggregation under flow conditions
    Dong, Jing-fei
    Cruz, Miguel A.
    Aboulfatova, Khatira
    Martin, Cecilia
    Choi, Hiuwan
    Bergeron, Angela L.
    Martini, Sheryl R.
    Kroll, Michael H.
    Kent, Thomas A.
    [J]. THROMBOSIS AND HAEMOSTASIS, 2008, 99 (03) : 586 - 593
  • [3] Anti-inflammatory interventions in pregnancy: Now and the future
    Elovitz, Michal A.
    [J]. SEMINARS IN FETAL & NEONATAL MEDICINE, 2006, 11 (05) : 327 - 332
  • [4] Short- and long-term changes in plasma inflammatory markers associated with preeclampsia
    Freeman, DJ
    McManus, F
    Brown, EA
    Cherry, L
    Norrie, J
    Ramsay, JE
    Clark, P
    Walker, ID
    Sattar, N
    Greer, IA
    [J]. HYPERTENSION, 2004, 44 (05) : 708 - 714
  • [5] Pre-eclampsia is associated with dendritic cell recruitment into the uterine decidua
    Huang, S. J.
    Chen, C-P
    Schatz, F.
    Rahman, M.
    Abrahams, V. M.
    Lockwood, C. J.
    [J]. JOURNAL OF PATHOLOGY, 2008, 214 (03) : 328 - 336
  • [6] C-reactive protein is elevated 30 years after eclamptic pregnancy
    Hubel, Carl A.
    Powers, Robert W.
    Snaedal, Sunna
    Gammill, Hilary S.
    Ness, Roberta B.
    Roberts, James M.
    Arngrimsson, Reynir
    [J]. HYPERTENSION, 2008, 51 (06) : 1499 - 1505
  • [7] Modulation of adjuvant arthritis in the rat by 2-methoxyestradiol: An effect independent of an anti-angiogenic action
    Issekutz, Andrew C.
    Sapru, Kusum
    [J]. INTERNATIONAL IMMUNOPHARMACOLOGY, 2008, 8 (05) : 708 - 716
  • [8] Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia
    Kanasaki, Keizo
    Palmsten, Kristin
    Sugimoto, Hikaru
    Ahmad, Shakil
    Hamano, Yuki
    Xie, Liang
    Parry, Samuel
    Augustin, Hellmut G.
    Gattone, Vincent H., Jr.
    Folkman, Judah
    Strauss, Jerome F.
    Kalluri, Raghu
    [J]. NATURE, 2008, 453 (7198) : 1117 - U12
  • [9] Comparative analysis of the maternal and umbilical interleukin-8 levels in normal pregnancies and in pregnancies complicated by preeclampsia with intrauterine normal growth and intrauterine growth retardation
    Laskowska, Marzena
    Laskowska, Katarzyna
    Leszczynska-Gorzelaw, Bena
    Oleszczuk, Jan
    [J]. JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2007, 20 (07) : 527 - 532
  • [10] Magnesium and the inflammatory response: Potential physiopathological implications
    Mazur, Andrzej
    Maier, Jeanette A. M.
    Rock, Edmond
    Gueux, Elyett
    Nowacki, Wojciech
    Rayssiguier, Yves
    [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2007, 458 (01) : 48 - 56
12