Intersection of immune checkpoints and CD8+ T cell noncytolytic suppression of HIV-1 infection: putting on the brakes versus the nuclear option

被引：0
作者：
Zaunders, John [1 ]
机构：
[1] St Vincents Hosp, Ctr Appl Med Res, Sydney, NSW 2010, Australia
来源：
AIDS | 2019年 / 33卷 / 03期
关键词：
CYTOTOXIC GRANULES; EXPRESSION; DEFINES; MEMORY; PD-1; PROLIFERATION; LYMPHOCYTES; PERFORIN; RECEPTOR; TISSUE;
D O I：
10.1097/QAD.0000000000002069
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：581 / 583
页数：3
相关论文
共 50 条
  • [21] Properties of HTLV-I transformed CD8+ T-cells in response to HIV-1 infection
    Gulzar, N.
    Shroff, A.
    Buberoglu, B.
    Klonowska, D.
    Kim, J. E.
    Copeland, K. F. T.
    VIROLOGY, 2010, 406 (02) : 302 - 311
  • [22] Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4+ and CD8+ T cell turnover in HIV-infected patients
    Lempicki, RA
    Kovacs, JA
    Baseler, MW
    Adelsberger, JW
    Dewar, RL
    Natarajan, V
    Bosche, MC
    Metcalf, JA
    Stevens, RA
    Lambert, LA
    Alvord, WG
    Polis, MA
    Davey, RT
    Dimitrov, DS
    Lane, HC
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (25) : 13778 - 13783
  • [23] Phenotypic Characterization of HIV-Specific CD8+ T Cells during Early and Chronic Infant HIV-1 Infection
    Slyker, Jennifer A.
    John-Stewart, Grace C.
    Dong, Tao
    Lohman-Payne, Barbara
    Reilly, Marie
    Atzberger, Ann
    Taylor, Stephen
    Maleche-Obimbo, Elizabeth
    Mbori-Ngacha, Dorothy
    Rowland-Jones, Sarah L.
    PLOS ONE, 2011, 6 (05):
  • [24] Initial HIV-1 Antigen-Specific CD8+ T Cells in Acute HIV-1 Infection Inhibit Transmitted/Founder Virus Replication
    Freel, Stephanie A.
    Picking, Ralph A.
    Ferrari, Guido
    Ding, Haitao
    Ochsenbauer, Christina
    Kappes, John C.
    Kirchherr, Jennifer L.
    Soderberg, Kelly A.
    Weinhold, Kent J.
    Cunningham, Coleen K.
    Denny, Thomas N.
    Crump, John A.
    Cohen, Myron S.
    McMichael, Andrew J.
    Haynes, Barton F.
    Tomaras, Georgia D.
    JOURNAL OF VIROLOGY, 2012, 86 (12) : 6835 - 6846
  • [25] Alteration of CD8+T cell effector diversity during HIV-1 infection with discordant normalization in effective antiretroviral therapy
    Onlamoon, Nattawat
    Sukapirom, Kasama
    Polsrila, Korakot
    Ammaranond, Palanee
    Pattanapanyasat, Kovit
    CYTOMETRY PART B-CLINICAL CYTOMETRY, 2012, 82B (01) : 35 - 42
  • [26] Emergence of a distinct HIV-specific IL-10-producing CD8+ T-cell subset with immunomodulatory functions during chronic HIV-1 infection
    Clutton, Genevieve
    Yang, Hongbing
    Hancock, Gemma
    Sande, Nellia
    Holloway, Cameron
    Angus, Brian
    von Delft, Annette
    Barnes, Eleanor
    Borrow, Persephone
    Pellegrino, Pierre
    Williams, Ian
    McMichael, Andrew
    Dorrell, Lucy
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2013, 43 (11) : 2875 - 2885
  • [27] Immune-Checkpoint Blockade Opposes CD8+ T-cell Suppression in Human and Murine Cancer
    Pfannenstiel, Lukas W.
    Diaz-Montero, C. Marcela
    Tian, Ye F.
    Scharpf, Joseph
    Ko, Jennifer S.
    Gastman, Brian R.
    CANCER IMMUNOLOGY RESEARCH, 2019, 7 (03) : 510 - 525
  • [28] HIV-1 infection and the lack of viral control are associated with greater expression of interleukin-21 receptor on CD8+ T cells
    Dalel, Jama
    Ung, Seng K.
    Hayes, Peter
    Black, S. Lucas
    Joseph, Sarah
    King, Deborah F.
    Makinde, Julia
    Gilmour, Jill
    AIDS, 2021, 35 (08) : 1167 - 1177
  • [29] CD4 and CD8 T Cell Immune Activation during Chronic HIV Infection: Roles of Homeostasis, HIV, Type I IFN, and IL-7
    Catalfamo, Marta
    Wilhelm, Christopher
    Tcheung, Lueng
    Proschan, Michael
    Friesen, Travis
    Park, Jung-Hyun
    Adelsberger, Joseph
    Baseler, Michael
    Maldarelli, Frank
    Davey, Richard
    Roby, Gregg
    Rehm, Catherine
    Lane, Clifford
    JOURNAL OF IMMUNOLOGY, 2011, 186 (04) : 2106 - 2116
  • [30] Changing roles of CD3+CD8low T cells in combating HIV-1 infection
    Zhang, Xin
    Wang, Xiuwen
    Qin, Ling
    Lu, Xiaofan
    Liu, Zhiying
    Li, Zhen
    Yuan, Lin
    Wang, Rui
    Jin, Junyan
    Ma, Zhenglai
    Wu, Hao
    Zhang, Yonghong
    Zhang, Tong
    Su, Bin
    CHINESE MEDICAL JOURNAL, 2023, 136 (04) : 433 - 445
12345