Pandemic influenza A (H1N1) 2009: the experience of the first six months

被引：11

作者：

Maritz, Jean ^{[1
]}

Maree, Leana

Preiser, Wolfgang

机构：

[1] Natl Hlth Lab Serv, Dept Pathol, Div Med Virol, ZA-7505 Cape Town, South Africa

来源：

CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 2010年 / 48卷 / 01期

关键词：

H1N1; influenza A virus; pandemic; review; swine flu; CRITICALLY-ILL PATIENTS; UNITED-STATES; RESPIRATORY-FAILURE; IN-VITRO; A(H1N1); OSELTAMIVIR; VIRUS; TRANSMISSION; HOSPITALIZATION; PATHOGENESIS;

D O I：

10.1515/CCLM.2010.023

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

After a break of 41 years, 2009 saw the first influenza pandemic of the 21st century caused by a triple-reassortant influenza A (H1N1) virus. The current estimated case fatality rate is lower than that of previous influenza pandemics, but this may change as the pandemic evolves. Illness frequently occurs in previously healthy, young adults with a wide range of clinical presentations. The majority of circulating pandemic viruses remain susceptible to neuraminidase inhibitors, although all strains are intrinsically resistant to the adamantanes. Monovalent vaccines against the pandemic strain are available in both live attenuated and inactivated forms. This review aims to summarise important virological, epidemiological and clinical aspects of the pandemic influenza A (H1N1) virus for physicians and other clinical personnel. Clin Chem Lab Med 2010; 48: 11-21.

引用

页码：11 / 21

页数：11

共 77 条

[41]

Kelly H, 2009, EUROSURVEILLANCE, V14, P33

[42] Neurological and neuromuscular disease as a risk factor for respiratory failure in children hospitalized with influenza infection [J].

Keren, R ;

Zaoutis, TE ;

Bridges, CB ;

Herrera, G ;

Watson, BM ;

Wheeler, AB ;

Licht, DJ ;

Luan, XQ ;

Coffin, SE .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 294 (17) :2188-2194

[43] Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada [J].

Kumar, Anand ;

Zarychanski, Ryan ;

Pinto, Ruxandra ;

Cook, Deborah J. ;

Marshall, John ;

Lacroix, Jacques ;

Stelfox, Tom ;

Bagshaw, Sean ;

Choong, Karen ;

Lamontagne, Francois ;

Turgeon, Alexis F. ;

Lapinsky, Stephen ;

Ahern, Stephane P. ;

Smith, Orla ;

Siddiqui, Faisal ;

Jouvet, Philippe ;

Khwaja, Kosar ;

McIntyre, Lauralyn ;

Menon, Kusum ;

Hutchison, Jamie ;

Hornstein, David ;

Joffe, Ari ;

Lauzier, Francois ;

Singh, Jeffrey ;

Karachi, Tim ;

Wiebe, Kim ;

Olafson, Kendiss ;

Ramsey, Clare ;

Sharma, Sat ;

Dodek, Peter ;

Meade, Maureen ;

Hall, Richard ;

Fowler, Robert A. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2009, 302 (17) :1872-1879

[44] Viral zoonoses - A threat under control? [J].

Ludwig, B ;

Kraus, FB ;

Allwinn, R ;

Doerr, HW ;

Preiser, W .

INTERVIROLOGY, 2003, 46 (02) :71-78

[45] Transmission and Pathogenesis of Swine-Origin 2009 A(H1N1) Influenza Viruses in Ferrets and Mice [J].

Maines, Taronna R. ;

Jayaraman, Akila ;

Belser, Jessica A. ;

Wadford, Debra A. ;

Pappas, Claudia ;

Zeng, Hui ;

Gustin, Kortney M. ;

Pearce, Melissa B. ;

Viswanathan, Karthik ;

Shriver, Zachary H. ;

Raman, Rahul ;

Cox, Nancy J. ;

Sasisekharan, Ram ;

Katz, Jacqueline M. ;

Tumpey, Terrence M. .

SCIENCE, 2009, 325 (5939) :484-487

[46] Pandemic H1N1 infection in pregnant women in the USA [J].

Mangtani, Punam ;

Mak, Tippi K. ;

Pfeifer, Dina .

LANCET, 2009, 374 (9688) :429-430

[47] Influenza receptors, polymerase and host range [J].

Matrosovich, M. ;

Stech, J. ;

Klenk, H. Dieter .

REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES, 2009, 28 (01) :203-217

[48] Lung Pathology in Fatal Novel Human Influenza A (H1N1) Infection [J].

Mauad, Thais ;

Hajjar, Ludhmila A. ;

Callegari, Giovanna D. ;

da Silva, Luiz F. F. ;

Schout, Denise ;

Galas, Filomena R. B. G. ;

Alves, Venancio A. F. ;

Malheiros, Denise M. A. C. ;

Auler, Jose O. C., Jr. ;

Ferreira, Aurea F. ;

Borsato, Marcela R. L. ;

Bezerra, Stephania M. ;

Gutierrez, Paulo S. ;

Caldini, Elia T. E. G. ;

Pasqualucci, Carlos A. ;

Dolhnikoff, Marisa ;

Saldiva, Paulo H. N. .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2010, 181 (01) :72-79

[49] Antiviral therapy and outcomes of influenza requiring hospitalization in Ontario, Canada [J].

McGeer, Allison ;

Green, Karen A. ;

Plevneshi, Agron ;

Shigayeva, Altynay ;

Siddiqi, Nilofar ;

Raboud, Janet ;

Low, Donald E. .

CLINICAL INFECTIOUS DISEASES, 2007, 45 (12) :1568-1575

[50] Zanamivir prophylaxis: An effective strategy for the prevention of influenza types A and B within households [J].

Monto, AS ;

Pichichero, ME ;

Blanckenberg, SJ ;

Ruuskanen, O ;

Cooper, C ;

Fleming, DM ;

Kerr, C .

JOURNAL OF INFECTIOUS DISEASES, 2002, 186 (11) :1582-1588

← 1 2 3 4 5 6 7 8 →