Proton magnetic resonance spectroscopy in a case of subacute sclerosing panencephalitis

被引：8

作者：

Kato, Z ^{[1
]}

Saito, K ^{[1
]}

Yamada, M ^{[1
]}

Asano, T ^{[1
]}

Kondo, N ^{[1
]}

机构：

[1] Gifu Univ, Sch Med, Dept Pediat, Gifu 5008705, Japan

来源：

JOURNAL OF CHILD NEUROLOGY | 2002年 / 17卷 / 10期

关键词：

D O I：

10.1177/08830738020170101809

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Subacute sclerosing panencephalitis is an encephalopathy caused by a persistent measles virus infection. We examined a 13-year-old girl with subacute sclerosing panencephalitis and performed a magnetic resonance spectroscopic study to evaluate the in vivo pathophysiologic abnormality. The results suggested the occurrence of inflammatory processes and glial proliferation prior to neuronal loss even in magnetic resonance imaging (MRI)-negative regions as well as in MRI-positive regions. The additional resonance peaks were also detected, but further studies should be performed to determine the precise pathophysiologic mechanisms. Novel in vivo modalities such as spectroscopy would be useful as a tool to measure responses to therapy.

引用

页码：788 / 790

页数：3

共 6 条

[1] MRI findings in subacute sclerosing panencephalitis [J].