Stroke Volume Variation Monitoring to Minimize Blood Loss in Hepatocellular Carcinoma Resection

Background/Aim: We aimed to evaluate the correlation between stroke volume variation (SVV) and intraoperative blood loss (IBL) in hepatocellular carcinoma (HCC) resection and examine the perioperative utility of SVV-based management. Patients and Methods: Ninety-five patients who underwent partial or sub-segmental hepatectomy for HCC between 2013 and 2019 at the University of Yamanashi Hospital were retrospectively analyzed. A correlation analysis between IBL and SW was performed, and then all cases were divided into three groups: high, middle, and low-SVV groups. Perioperative short-term outcomes based on SW groups were analyzed. Results: There was a weak but significant negative correlation between SVV and IBL (rho=-0.372, p<0.001). Comparative analysis revealed that low-SVV was associated with a high incidence of postoperative complications and blood transfusion (p=0.018 and 0.037, respectively), and high-SVV was not related with postoperative complications. Conclusion: SVV-based management is a significant and feasible strategy to achieve safe and exact surgical resection of HCC.