Lyme borreliosis

被引：21

作者：

Schnarr, Sebastian

Franz, Juliane K.

Krause, Andreas

Zeidler, Henning ^{[1
]}

机构：

[1] Hannover Med Sch, Dept Internal Med, Div Rheumatol, D-3000 Hannover, Germany

[2] Rheumaklin Ostbayern, Bad Fuessing, Germany

[3] Privatklin Pk, Bad Schinznach, Switzerland

[4] Immanuel Hosp, Rheumakliniken Berlin Burch & Berlin Wannsee, Berlin, Germany

来源：

BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY | 2006年 / 20卷 / 06期

关键词：

Lyme disease; Lyme borreliosis; Borrelia burgdorferi; epidemiology; pathogenesis; diagnosis; therapy; prevention; vaccine;

D O I：

10.1016/j.berh.2006.08.006

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Lyme borreliosis is a tick-borne infectious disease caused by the spirochaetes Borrelia burgdorferi, B. garinii and B. aftelii. It comprises a wide spectrum of symptoms affecting skin, musculoskeletal system, heart, eyes, central and peripheral nervous system. The diagnosis is based on clinical findings in combination with detection of specific IgM and/or IgG antibodies. Diagnostic problems arise from patients with non-specific symptoms and positive IgG antibody detection. Adequate antibiotic therapy cures more than 90% of the patients. However, in some patients repeated therapy is necessary and a small number of patients develop chronic arthritis or other features. While there is currently no vaccine available, prevention of tick bite is the most effective prophylaxis.

引用

页码：1099 / 1118

页数：20

共 78 条

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