CuI as reusable catalyst for the Biginelli reaction

被引：81

作者：

Kalita, Hima Rani ^{[1
]}

Phukan, Prodeep ^{[1
]}

机构：

[1] Gauhati Univ, Dept Chem, Gauhati 781014, Assam, India

来源：

CATALYSIS COMMUNICATIONS | 2007年 / 8卷 / 02期

关键词：

Biginelli reaction; CuI; aldehyde; ethyl acetoacetate; urea;

D O I：

10.1016/j.catcom.2006.06.004

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

An improved protocol for the Biginelli reaction using CuI as a reusable catalyst is described. The synthesis of 3,4-dihydropyrimidin-2(IH)-ones was achieved in acetonitrile, water and under solvent-free condition. After separation of product from the reaction mixture, the mother liquor (acetonitrile or water) containing the catalyst was reused two times without any loss of activity. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：179 / 182

页数：4

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