Perinatal risk factors associated with skin infection hospitalisation in Western Australian Aboriginal and Non-Aboriginal children

被引：4

作者：

Barnes, Rosanne ^{[1
]}

Bowen, Asha C. ^{[1
,2
,3
,4
]}

Walker, Roz ^{[1
,5
]}

Tong, Steven Y. C. ^{[4
,6
,7
]}

McVernon, Jodie ^{[7
,8
,9
,10
]}

Campbell, Patricia T. ^{[7
,8
]}

Fathima, Parveen ^{[1
]}

de Klerk, Nicholas H. ^{[1
]}

Wu, Yue ^{[1
]}

Blyth, Christopher C. ^{[1
,2
,3
]}

Carapetis, Jonathan R. ^{[1
,2
,3
]}

Moore, Hannah C. ^{[1
]}

机构：

[1] Univ Western Australia, Wesfarmers Ctr Vaccines & Infect Dis, Telethon Kids Inst, Nedlands, WA, Australia

[2] Univ Western Australia, Sch Med, Perth, WA, Australia

[3] Perth Childrens Hosp, Dept Infect Dis, Nedlands, WA, Australia

[4] Charles Darwin Univ, Menzies Sch Hlth Res, Casuarina, NT, Australia

[5] Univ Western Australia, Ctr Child Hlth Res, Nedlands, WA, Australia

[6] Royal Melbourne Hosp, Peter Doherty Inst Infect & Immun, Victorian Infect Dis Serv, Melbourne, Vic, Australia

[7] Univ Melbourne, Peter Doherty Inst Infect & Immun, Doherty Dept, Melbourne, Vic, Australia

[8] Royal Melbourne Hosp, Peter Doherty Inst Infect & Immun, Victorian Infect Dis Reference Lab Epidemiol Unit, Melbourne, Vic, Australia

[9] Univ Melbourne, Ctr Epidemiol & Biostat, Melbourne Sch Populat & Global Hlth, Parkville, Vic, Australia

[10] Royal Childrens Hosp, Murdoch Childrens Res Inst, Infect & Immun Theme, Parkville, Vic, Australia

来源：

PAEDIATRIC AND PERINATAL EPIDEMIOLOGY | 2019年 / 33卷 / 05期

基金：

澳大利亚国家健康与医学研究理事会; 英国医学研究理事会;

关键词：

children; hospitalisations; record linkage; skin infection; NEW-ZEALAND; PREVALENCE; SCABIES; LINKAGE; HEALTH;

D O I：

10.1111/ppe.12573

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background Hospitalisation with skin infection in Western Australian (WA) Aboriginal children is common, with the highest rates in infants and children from remote WA. Objective We aimed to quantify infant, maternal, and sociodemographic risk factors for skin infection hospitalisation in WA children, focussing on Aboriginal children aged We conducted a retrospective population-based cohort study with linked perinatal and hospitalisation data on WA-born children (1996-2012), of whom 31 348 (6.7%) were Aboriginal. We used Cox regression to calculate adjusted hazard ratios and associated population attributable fractions (PAFs) for perinatal factors attributed to first hospitalisation with skin infection. To identify specific risk factors for early-onset infection, we further restricted the cohort to infants aged <1 year. Results Overall, 5439 (17.4%) Aboriginal and 6750 (1.5%) non-Aboriginal children were hospitalised at least once with a skin infection. Aboriginal infants aged <1 year had the highest skin infection hospitalisation rate (63.2 per 1000 child-years). The strongest risk factors in Aboriginal children aged <17 years were socio-economic disadvantage, very remote location at birth, and multi-parity (>= 3 previous pregnancies) accounting for 24%, 23%, and 15% of skin infection hospitalisations, respectively. Other risk factors included maternal age <20 years, maternal smoking during pregnancy, and low birthweight. Conclusions We have quantified the relative influence of perinatal risk factors associated with skin infection hospitalisations in WA children, providing measures indicating which factors have the potential to reduce the most hospitalisations. Our evidence not only supports existing calls for substantial government investment in addressing underlying social and environmental barriers to healthy skin in WA Aboriginal children but also identifies potential areas to target health promotion messaging at individuals/families on maternal smoking during pregnancy and skin hygiene for families.

引用

页码：374 / 383

页数：10

共 29 条

[1] Hospital admissions for skin infections among Western Australian children and adolescents from 1996 to 2012 [J].