Perioperative and post-operative complications of transvaginal ultrasound-guided oocyte retrieval:: prospective study of >1000 oocyte retrievals

被引:74
作者
Ludwig, A. K. [1 ]
Glawatz, M. [1 ]
Griesinger, G. [1 ]
Diedrich, K. [1 ]
Ludwig, M. [1 ]
机构
[1] Univ Schleswig Holstein, Dept Obstet & Gynaecol, D-23538 Lubeck, Germany
关键词
bleeding; complications; oocyte aspiration; oocyte retrieval; IN-VITRO FERTILIZATION; INVITRO FERTILIZATION; CLINICAL COMPLICATIONS; EMBRYO-TRANSFER; IVF; SECONDARY; RECOVERY;
D O I
10.1093/humrep/del278
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
BACKGROUND: Although transvaginal ultrasound-guided oocyte retrievals (OR) are performed routinely worldwide, there is very little systematic data about its complications. METHODS: We performed a prospective cohort study following the perioperative and post-operative complications of over 1058 ORs. Additionally, we assessed the pain experienced during the OR. RESULTS: A total of 1166 OR were performed during the study period, of which 1058 (90.7%) ORs were included prospectively. Incomplete data meant that the remaining 9.3% were excluded. No complications were caused by sedation or general anaesthesia. Vaginal bleeding was observed in 2.8% of procedures, without any cases of intra-abdominal bleeding. An injury of pelvic structures (a ureteral lesion) occurred in one case. No case of pelvic infection, but one case of unexplained fever, was observed. A severe ovarian hyperstimulation syndrome (OHSS) occurred in 2.7% of cases. Although most patients tolerated the OR well, 3% of patients experienced severe to very severe pain after the OR and 2% of patients were still suffering from severe pain 2 days after the procedure. The pain level increased with the number of oocytes retrieved. About 0.7% of patients required hospitalization for pain treatment. CONCLUSIONS: Patients can be reassured that overall OR is a safe procedure. However, patients have to be counselled about the minor risks of the OR. The literature on complications is reviewed in the article.
引用
收藏
页码:3235 / 3240
页数:6
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