Towards an Automatic Lung Cancer Screening System in Low Dose Computed Tomography

被引:11
作者
Aresta, Guilherme [1 ,2 ]
Araujo, Teresa [1 ,2 ]
Jacobs, Colin [6 ]
van Ginneken, Bram [6 ]
Cunha, Antonio [1 ,3 ,4 ]
Ramos, Isabel [5 ]
Campilho, Aurelio [1 ,2 ]
机构
[1] INESC TEC, P-4200 Porto, Portugal
[2] Univ Porto, Fac Engn, P-4200465 Porto, Portugal
[3] Univ Minho, P-5001801 Vila Real, Portugal
[4] Alto Douro, P-5001801 Vila Real, Portugal
[5] Univ Porto, Fac Med, P-4200319 Porto, Portugal
[6] Radboud Univ Nijmegen, Med Ctr, NL-6525 Nijmegen, Netherlands
来源
IMAGE ANALYSIS FOR MOVING ORGAN, BREAST, AND THORACIC IMAGES | 2018年 / 11040卷
关键词
Computer aided diagnosis; Lung cancer; Low dose computed tomography images; Screening; Deep learning; IMAGE DATABASE CONSORTIUM; PULMONARY NODULES; MORTALITY;
D O I
10.1007/978-3-030-00946-5_31
中图分类号
TP301 [理论、方法];
学科分类号
081202 ;
摘要
We propose a deep learning-based pipeline that, given a low-dose computed tomography of a patient chest, recommends if a patient should be submitted to further lung cancer assessment. The algorithm is composed of a nodule detection block that uses the object detection framework YOLOv2, followed by a U-Net based segmentation. The found structures of interest are then characterized in terms of diameter and texture to produce a final referral recommendation according to the National Lung Screen Trial (NLST) criteria. Our method is trained using the public LUNA16 and LIDC-IDRI datasets and tested on an independent dataset composed of 500 scans from the Kaggle DSB 2017 challenge. The proposed system achieves a patient-wise recall of 89% while providing an explanation to the referral decision and thus may serve as a second opinion tool to speed-up and improve lung cancer screening.
引用
收藏
页码:310 / 318
页数:9
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