Biological Lasers for Biomedical Applications

被引：136

作者：

Chen, Yu-Cheng ^{[1
,2
]}

Fan, Xudong ^{[2
]}

机构：

[1] Nanyang Technol Univ, Sch Elect & Elect Engn, 50 Nanyang Ave, Singapore 639798, Singapore

[2] Univ Michigan, Dept Biomed Engn, 1101 Beal Ave, Ann Arbor, MI 48109 USA

来源：

ADVANCED OPTICAL MATERIALS | 2019年 / 7卷 / 17期

基金：

美国国家科学基金会;

关键词：

bioimaging; biological lasers; biomedical sensing; labeling; mapping; microresonators; nanoresonators; tracking; OPTOFLUIDIC LASERS; CELL; MICROLASERS; CANCER;

D O I：

10.1002/adom.201900377

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

A biolaser utilizes biological materials as part of its gain medium and/or part of its cavity. It can also be a micro- or nanosized laser embedded/integrated within biological materials. The biolaser employs lasing emission rather than regular fluorescence as the sensing signal and therefore has a number of unique advantages that can be explored for broad applications in biosensing, labeling, tracking, contrast agent development, and bioimaging. This article reports on the progress in biolasers with focus on the work done in the past five years. In the end, the possible future directions of the biolaser are discussed.

引用

页数：14

共 102 条

[21]

Fan XD, 2014, NAT METHODS, V11, P141, DOI [10.1038/NMETH.2805, 10.1038/nmeth.2805]

[22] Organic-Nanowire-SiO2 Core Shell Microlasers with Highly Polarized and Narrow Emissions for Biological Imaging [J].

Feng, Changfu ;

Xu, Zhenzhen ;

Wang, Xu ;

Yang, Hongjuan ;

Zheng, Lemin ;

Fu, Hongbing .

ACS APPLIED MATERIALS & INTERFACES, 2017, 9 (08) :7385-7391

[23] Continuous-wave upconverting nanoparticle microlasers [J].

Fernandez-Bravo, Angel ;

Yao, Kaiyuan ;

Barnard, Edward S. ;

Borys, Nicholas J. ;

Levy, Elizabeth S. ;

Tian, Bining ;

Tajon, Cheryl A. ;

Moretti, Luca ;

Altoe, M. Virginia ;

Aloni, Shaul ;

Beketayev, Kenes ;

Scotognella, Francesco ;

Cohen, Bruce E. ;

Chan, Emory M. ;

Schuck, P. James .

NATURE NANOTECHNOLOGY, 2018, 13 (07) :572-577

[24] Non-obstructive intracellular nanolasers [J].

Fikouras, Alasdair H. ;

Schubert, Marcel ;

Karl, Markus ;

Kumar, Jothi D. ;

Powis, Simon J. ;

Di Falco, Andrea ;

Gather, Malte C. .

NATURE COMMUNICATIONS, 2018, 9

[25] Gain-Based Mechanism for pH Sensing Based on Random Lasing [J].

Gaio, Michele ;

Caixeiro, Soraya ;

Marelli, Benedetto ;

Omenetto, Fiorenzo G. ;

Sapienza, Riccardo .

PHYSICAL REVIEW APPLIED, 2017, 7 (03)

[26] Spaser as a biological probe [J].

Galanzha, Ekaterina I. ;

Weingold, Robert ;

Nedosekin, Dmitry A. ;

Sarimollaoglu, Mustafa ;

Nolan, Jacqueline ;

Harrington, Walter ;

Kuchyanov, Alexander S. ;

Parkhomenko, Roman G. ;

Watanabe, Fumiya ;

Nima, Zeid ;

Biris, Alexandru S. ;

Plekhanov, Alexander I. ;

Stockman, Mark I. ;

Zharov, Vladimir P. .

NATURE COMMUNICATIONS, 2017, 8

[27] Controlled assembly of organic whispering-gallery- mode microlasers as highly sensitive chemical vapor sensors [J].

Gao, Miaomiao ;

Wei, Cong ;

Lin, Xianqing ;

Liu, Yuan ;

Hu, Fengqin ;

Zhao, Yong Sheng .

CHEMICAL COMMUNICATIONS, 2017, 53 (21) :3102-3105

[28] Proton-Controlled Organic Microlaser Switch [J].

Gao, Zhenhua ;

Zhang, Wei ;

Yan, Yongli ;

Yi, Jun ;

Dong, Haiyun ;

Wang, Kang ;

Yao, Jiannian ;

Zhao, Yong Sheng .

ACS NANO, 2018, 12 (06) :5734-5740

[29] Bio-optimized energy transfer in densely packed fluorescent protein enables near-maximal luminescence and solid-state lasers [J].

Gather, Malte C. ;

Yun, Seok Hyun .

NATURE COMMUNICATIONS, 2014, 5

[30]

Gather MC, 2011, NAT PHOTONICS, V5, P406, DOI [10.1038/nphoton.2011.99, 10.1038/NPHOTON.2011.99]

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